Protein detail
NPTXR
Neuronal pentraxin receptor
Entry name NPTXR | UniProt ID | EVMP score 0.38 |
Frequency 3 | Transmembrane count 1 | Protein classification Plasma proteinsPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Neuronal pentraxin receptor
Protein Class
Plasma proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Transmembrane
3..23; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Description
Neuronal pentraxin receptor
Chromosome
22
Position
38818452-38844028
Frequency
3
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
- M68 Pid rhoa reg pathway
- M186 Pid pdgfrb pathway
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
11 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | CellCellInteractions | No | Yes | No | No | No |
Page 2 of 2Previous
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyPolymer PrecipitationImmunoaffinity Capture | Mass spectrometryMass spectrometry [LTQ-FT Ultra] | 42 | 401894973606464738113368286801524046519534815502351197783732247535359923333044783649718434064677268265363889596231382537335925003447350538891077375638573891792632560723411284893291698641307968361468343922366133309826408407013180595833893753386070623223097038207106387165123283573534576246372045153900170037438638392070473792675641068253 |
Sequence, Structure & Domains
Sequences
Length
500
Mass
52,846
Sequence
MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGADNASVASGAAASPGPQRSLSALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMADGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA
3D Structural Models
Domain & Motif Annotations
Compositional Bias
42..63; Low complexity
Domain (FT)
292..494; Pentraxin (PTX)
Region
42..81; Disordered; 162..183; Disordered
Clinical Relevance
Drugs
Antibody
Interaction Protein
ENSG00000106236
Interaction Count
1
Interaction Dataset
biogrid_bioplex