Protein detail
TM50A
Transmembrane protein 50A (Small membrane protein 1)
Entry name TM50A | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 3 | Transmembrane count 4 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 50A (Small membrane protein 1)
Protein Function
Transporters
Transmembrane
26..46; Helical; 58..78; Helical; 95..115; Helical; 126..146; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Supporting publications (n)
3
EVMP confidence score
0.28
Fluorescence & Localization
Tissue SpecificesophagusCell SpecificBasal keratinocytesSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell SpecificeosinophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function
Transporters
Cellular Component (4)
Molecular Function
Biological Process (3)
Canonical Pathways
M266 Pid ncadherin pathway
Mediation Categories
Other mediation
Relations & Evidence13
Ligand-Receptor Signaling (11)
11 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane_predicted | Phobius |
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Protein Complex Composition (1)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western blottingMORPH | 1 | 32089743 |
Sequence, Structure & Domains
Sequences
Length
157
Mass
17,400
Sequence
MSGFLEGLRCSECIDWGEKRNTIASIAAGVLFFTGWWIIIDAAVIYPTMKDFNHSYHACGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFVGFMLAFGSLIASMWILFGGYVAKEKDIVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ
Domain & Motif Annotations
Protein Families
UPF0220 family
Sequence Similarities
Belongs to the UPF0220 family.
Supporting Publications3
| PMID | Title | Related sentences |
|---|---|---|
| 37922300 | Proteomic profiling of urinary extracellular vesicles differentiates breast cancer patients from healthy women. | No related sentences available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |
| 39104279 | A Predictive Model for Initial Platinum-Based Chemotherapy Efficacy in Patients with Postoperative Epithelial Ovarian Cancer Using Tissue-Derived Small Extracellular Vesicles. | No related sentences available |