Protein detail
THY1
Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90)
Entry name THY1 | UniProt ID | EVMP score 0.38 |
Frequency 2 | Transmembrane count | Protein classification CD markersPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90)
Protein Class
CD markersPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins
Protein Function
- CD markers
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
CD90
Gene Description
Thy-1 cell surface antigen
Chromosome
11
Position
119415476-119424985
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecifickidneyBrain Regional Specificchoroid plexusCell SpecificBreast secretory cellsSingle-Nuclei Brain Specificchoroid plexus epithelial cellSecretome LocationIntracellular and membraneSecretome FunctionTransport
Function & Pathway
Protein Function
- CD markers
- Predicted intracellular proteins
Cellular Component
- GO:0005576 extracellular region
- GO:0005783 endoplasmic reticulum
- GO:0005886 plasma membrane
- GO:0005925 focal adhesion
- GO:0009897 external side of plasma membrane
- GO:0009986 cell surface
- GO:0016324 apical plasma membrane
- GO:0030425 dendrite
- GO:0030426 growth cone
- GO:0030673 axolemma
- GO:0032590 dendrite membrane
- GO:0032809 neuronal cell body membrane
- GO:0045121 membrane raft
- GO:0070062 extracellular exosome
- GO:0098793 presynapse
- GO:0098794 postsynapse
- GO:0098978 glutamatergic synapse
Molecular Function
Biological Process
Reactome
Canonical Pathways
M53 Pid integrin3 pathway
Mediation Categories
Adhesion and uptake mediationFusion and delivery mediationImmune mediationMetabolism mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
41 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane_peripheral | plasma_membrane_peripheral | CSPA | No | No | No | No | Yes |
| plasma_membrane_peripheral | plasma_membrane_peripheral | OmniPath | No | No | No | No | Yes |
| cell_surface | cell_surface | Surfaceome | No | No | No | No | Yes |
| cell_surface | cell_surface | connectomeDB2020 | No | No | No | No | Yes |
| cell_surface | cell_surface | OmniPath | No | No | No | No | Yes |
| ligand | ligand | ICELLNET | Yes | No | No | No | Yes |
| cell_adhesion | ligand | ICELLNET | Yes | No | No | No | Yes |
| adhesion_gpcr | ligand | ICELLNET | Yes | No | No | No | Yes |
| ligand | ligand | OmniPath | Yes | No | No | No | Yes |
| receptor | receptor | connectomeDB2020 | No | Yes | No | No | Yes |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Western blotting | 1 | 37922300 |
Sequence, Structure & Domains
Sequences
Length
161
Mass
17,935
Sequence
MNLAISIALLLTVLQVSRGQKVTSLTACLVDQSLRLDCRHENTSSSPIQYEFSLTRETKKHVLFGTVGVPEHTYRSRTNFTSKYNMKVLYLSAFTSKDEGTYTCALHHSGHSPPISSQNVTVLRDKLVKCEGISLLAQNTSWLLLLLLSLSLLQATDFMSL
3D Structural Models
Domain & Motif Annotations
Domain (FT)
20..126; Ig-like V-type