Protein detail
CD1A
T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
Protein symbol CD1A | UniProt ID | EVMP score 0.38 |
Frequency | Transmembrane count 1 | Protein classification CD markersPredicted membrane proteins |
Basic Information
Protein Names
T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
Protein Class
CD markersPredicted membrane proteins
Protein Function
CD markers
Transmembrane
301..321; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CD1
Gene Description
CD1a molecule
Chromosome
1
Position
158254424-158258269
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificesophagusCell SpecificCytotrophoblastsSingle-Nuclei Brain Specificendothelial cell
Function & Pathway
Protein Function
CD markers
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Clinical-translation mediationFusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
40 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | CellTalkDB | No | Yes | No | Yes | No |
| receptor | receptor | Surfaceome | No | Yes | No | Yes | No |
| receptor | receptor | Ramilowski2015 | No | Yes | No | Yes | No |
| receptor | receptor | LRdb | No | Yes | No | Yes | No |
| ig_like | receptor | Almen2009 | No | Yes | No | Yes | No |
| cd1 | receptor | Almen2009 | No | Yes | No | Yes | No |
| ig | receptor | Surfaceome | No | Yes | No | Yes | No |
| receptor | receptor | OmniPath | No | Yes | No | Yes | No |
| ecm | ecm | MatrixDB | Yes | No | No | Yes | No |
| ecm | ecm | OmniPath | Yes | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 1 | 32230970 |
Sequence, Structure & Domains
Sequences
Length
327
Mass
37,077
Sequence
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC
3D Structural Models
Turn
59..62; 102..106; 192..194
Helix
69..72; 77..101; 152..154; 155..165; 169..180; 182..191; 195..198; 270..272; 283..285
Beta Strand
27..37; 40..49; 52..58; 63..68; 109..119; 129..135; 138..144; 147..150; 205..210; 218..231; 234..239; 248..254; 256..258; 260..269; 276..281; 290..294
3D Structure
X-ray crystallography (15)
Domain & Motif Annotations
Domain (FT)
184..291; Ig-like
Clinical Relevance
Related Diseases
Biomarker
Approved; Phase 1