Protein detail
CD48
CD48 antigen (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (TCT.1) (CD antigen CD48)
Protein symbol CD48 | UniProt ID | EVMP score 0.63 |
Frequency 10 | Transmembrane count | Protein classification CD markersPlasma proteinsPredicted membrane proteinsPredicted secreted proteinsTransporters |
Basic Information
Protein Names
CD48 antigen (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (TCT.1) (CD antigen CD48)
Protein Class
CD markersPlasma proteinsPredicted membrane proteinsPredicted secreted proteinsTransporters
Protein Function
- Predicted secreted proteins
- CD markers
- Transporters:Accessory Factors Involved in Transport
Ensembl
Entrez Gene Symbol
Gene Synonym
BCM1BLASThCD48mCD48SLAMF2
Gene Description
CD48 molecule
Chromosome
1
Position
160678746-160711831
Frequency
10
EVMP Score
0.63
Fluorescence & Localization
Cell SpecificLate primary spermatocytes
Function & Pathway
Protein Function
- Predicted secreted proteins
- CD markers
- Transporters:Accessory Factors Involved in Transport
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
- M277 Pid integrin a4b1 pathway
- M3468 Naba ecm regulators
- M5885 Naba matrisome associated
Mediation Categories
Fusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
43 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane | plasma_membrane | Cellinker | No | No | Yes | Yes | Yes |
| plasma_membrane | plasma_membrane | OmniPath | No | No | Yes | Yes | Yes |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | No | No | Yes | Yes | Yes |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | Yes | Yes | Yes |
| plasma_membrane_peripheral | plasma_membrane_peripheral | CSPA | No | No | Yes | Yes | Yes |
| plasma_membrane_peripheral | plasma_membrane_peripheral | OmniPath | No | No | Yes | Yes | Yes |
| secreted | secreted | UniProt_keyword | No | No | Yes | Yes | Yes |
| secreted | secreted | UniProt_location | No | No | Yes | Yes | Yes |
| secreted | secreted | OmniPath | No | No | Yes | Yes | Yes |
| cell_surface | cell_surface | Surfaceome | No | No | Yes | Yes | Yes |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
243
Mass
27,683
Sequence
MCSRGWDSCLALELLLLPLSLLVTSIQGHLVHMTVVSGSNVTLNISESLPENYKQLTWFYTFDQKIVEWDSRKSKYFESKFKGRVRLDPQSGALYISKVQKEDNSTYIMRVLKKTGNEQEWKIKLQVLDPVPKPVIKIEKIEDMDDNCYLKLSCVIPGESVNYTWYGDKRPFPKELQNSVLETTLMPHNYSRCYTCQVSNSVSSKNGTVCLSPPCTLARSFGVEWIASWLVVTVPTILGLLLT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P09326-1; Sequence=Displayed; Name=2; IsoId=P09326-2; Sequence=VSP_055598, VSP_055599
Alternative Sequence
129..169; DPVPKPVIKIEKIEDMDDNCYLKLSCVIPGESVNYTWYGDK -> GESGEPKSKSPLQWPQMDHCRASWEAWGTLGEEERKTSGQV (in isoform 2); 170..243; Missing (in isoform 2)
3D Structural Models
Turn
80..84; 89..91; 114..116
Helix
101..103
Beta Strand
34..36; 41..43; 51..61; 64..69; 74..76; 94..98; 105..113; 117..120; 126..128
3D Structure
NMR spectroscopy (1)
Domain & Motif Annotations
Domain (FT)
29..127; Ig-like C2-type 1; 132..212; Ig-like C2-type 2