Protein detail
KPSH1
Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)
Entry name KPSH1 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count | Protein classification EnzymesPredicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)
Protein Class (2)
EnzymesPredicted membrane proteins
Protein Function (3)
- ENZYME proteins:Transferases
- Enzymes
- Kinases:CAMK Ser/Thr protein kinases
Ensembl
Entrez Gene Symbol
Gene Description
Protein serine kinase H1
Chromosome
16
Position
67893254-67929676
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Tissue Specificadipose tissueCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificmyeloid DCBlood Lineage Specificdendritic cellsSecretome LocationIntracellular and membraneSecretome FunctionCell adhesion
Function & Pathway
Protein Function (3)
- ENZYME proteins:Transferases
- Enzymes
- Kinases:CAMK Ser/Thr protein kinases
Cellular Component (7)
Molecular Function (5)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence13
Ligand-Receptor Signaling (12)
12 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | scConnect | Yes | ||||
| transmembrane | transmembrane_predicted | Phobius |
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Sequence, Structure & Domains
Sequences
Length
424
Mass
48,035
Sequence
MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
Domain & Motif Annotations
Compositional Bias
385..398; Low complexity
Domain (FT)
98..355; Protein kinase
Region
56..80; Disordered; 378..407; Disordered
Protein Families (2)
- Protein kinase superfamily
- CAMK Ser/Thr protein kinase family
Sequence Similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Clinical Relevance
Disease Involvement (2)
Disease variantIntrahepatic cholestasis
Related Diseases
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 37322475 | Comprehensive profiling of extracellular vesicles in uveitis and scleritis enables biomarker discovery and mechanism exploration. | No related sentences available |