Protein detail

KPSH1

Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)

Protein symbol
KPSH1
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
EnzymesPredicted membrane proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)
Protein Class
EnzymesPredicted membrane proteins
Protein Function
  • ENZYME proteins:Transferases
  • Enzymes
  • Kinases:CAMK Ser/Thr protein kinases
Entrez Gene Symbol
Gene Description
Protein serine kinase H1
Chromosome
16
Position
67893254-67929676
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue Specificadipose tissueCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificmyeloid DCBlood Lineage Specificdendritic cellsSecretome LocationIntracellular and membraneSecretome FunctionCell adhesion
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

12 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorscConnectNoYesNoNoNo
transmembranetransmembrane_predictedPhobiusNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureWestern blottingELISA438731868407845294009834641201090
Sequence, Structure & Domains

Sequences

Length
424
Mass
48,035
Sequence
MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG

3D Structural Models

Domain & Motif Annotations

Compositional Bias
385..398; Low complexity
Domain (FT)
98..355; Protein kinase
Region
56..80; Disordered; 378..407; Disordered
Protein Families
  • Protein kinase superfamily
  • CAMK Ser/Thr protein kinase family
Sequence Similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Clinical Relevance
Disease Involvement
Disease variantIntrahepatic cholestasis