Protein detail
CD1D
Antigen-presenting glycoprotein CD1d (R3G1) (CD antigen CD1d)
Protein symbol CD1D | UniProt ID | EVMP score 0.25 |
Frequency 5 | Transmembrane count 1 | Protein classification Cancer-related genesCD markersPredicted membrane proteins |
Basic Information
Protein Names
Antigen-presenting glycoprotein CD1d (R3G1) (CD antigen CD1d)
Protein Class
Cancer-related genesCD markersPredicted membrane proteins
Protein Function
- Cancer-related genes:Mutated cancer genes
- CD markers
Transmembrane
302..322; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Description
CD1d molecule
Chromosome
1
Position
158178030-158186427
Frequency
5
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificintestineCell SpecificAstrocytes
Function & Pathway
Protein Function
- Cancer-related genes:Mutated cancer genes
- CD markers
Cellular Component
- GO:0005615 extracellular space
- GO:0005737 cytoplasm
- GO:0005764 lysosome
- GO:0005765 lysosomal membrane
- GO:0005783 endoplasmic reticulum
- GO:0005789 endoplasmic reticulum membrane
- GO:0005886 plasma membrane
- GO:0009897 external side of plasma membrane
- GO:0009986 cell surface
- GO:0010008 endosome membrane
- GO:0016323 basolateral plasma membrane
Molecular Function
Biological Process
Reactome
Mediation Categories
Adhesion and uptake mediationFusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
41 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | connectomeDB2020 | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| ligand | ligand | ICELLNET | Yes | No | No | Yes | No |
| ligand | ligand | LRdb | Yes | No | No | Yes | No |
| hla_recognition | ligand | ICELLNET | Yes | No | No | Yes | No |
| ligand | ligand | OmniPath | Yes | No | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Protein Organic Solvent Precipitation | Mass spectrometry | 1 | 32384937 |
Sequence, Structure & Domains
Sequences
Length
335
Mass
37,717
Sequence
MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
3D Structural Models
Turn
70..75; 124..126; 257..259; 271..273
Helix
23..25; 78..105; 158..166; 170..181; 183..194; 196..199; 284..286
Beta Strand
28..38; 41..50; 53..58; 60..64; 66..69; 112..122; 128..136; 139..145; 148..151; 206..211; 215..218; 219..232; 235..240; 241..243; 248..250; 261..270; 278..282; 291..294
3D Structure
X-ray crystallography (21)
Domain & Motif Annotations
Motif
331..334; Internalization signal
Domain (FT)
185..292; Ig-like