Protein detail
EVI2A
Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A)
Entry name EVI2A | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A)
Protein Class
Predicted membrane proteins
Transmembrane
134..154; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
EVDAEVI2
Gene Description
Ecotropic viral integration site 2A
Chromosome
17
Position
31316410-31321749
Supporting publications (n)
1
EVMP confidence score
0.53
Function & Pathway
Cellular Component
Molecular Function (2)
Biological Process (3)
Canonical Pathways
M237 Pid vegfr1 2 pathway
Mediation Categories
Other mediation
Relations & Evidence22
Ligand-Receptor Signaling (21)
21 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | OmniPath | Yes | ||||
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | Yes | ||||
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | Yes | ||||
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | Yes | ||||
| cell_surface | cell_surface | Surfaceome | Yes | ||||
| cell_surface | cell_surface | OmniPath | Yes | ||||
| receptor | receptor | CellCellInteractions | Yes | Yes | |||
| transmembrane | transmembrane_predicted | Phobius | Yes | ||||
| transmembrane_phobius | transmembrane_predicted | Almen2009 | Yes | ||||
| transmembrane_sosui | transmembrane_predicted | Almen2009 | Yes |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 38795909 |
Sequence, Structure & Domains
Sequences
Length
236
Mass
26,213
Sequence
MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P22794-1; Sequence=Displayed; Name=2; IsoId=P22794-2; Sequence=VSP_038859
Alternative Sequence
1; M -> MLLRSWFGNKDFQALPILARLPSM (in isoform 2)
Domain & Motif Annotations
Compositional Bias
218..236; Basic and acidic residues
Region
217..236; Disordered
Protein Families
EVI2A family
Sequence Similarities
Belongs to the EVI2A family.
Clinical Relevance
Disease Involvement
Proto-oncogene
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 28396511 | Database-augmented Mass Spectrometry Analysis of Exosomes Identifies Claudin 3 as a Putative Prostate Cancer Biomarker. | No related sentences available |