Protein detail
EVI2A
Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A)
Protein symbol EVI2A | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A)
Protein Class
Predicted membrane proteins
Transmembrane
134..154; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
EVDAEVI2
Gene Description
Ecotropic viral integration site 2A
Chromosome
17
Position
31316410-31321749
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Cellular Component
Biological Process
Canonical Pathways
M237 Pid vegfr1 2 pathway
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
21 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 38795909 |
Sequence, Structure & Domains
Sequences
Length
236
Mass
26,213
Sequence
MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P22794-1; Sequence=Displayed; Name=2; IsoId=P22794-2; Sequence=VSP_038859
Alternative Sequence
1; M -> MLLRSWFGNKDFQALPILARLPSM (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
218..236; Basic and acidic residues
Region
217..236; Disordered
Protein Families
EVI2A family
Sequence Similarities
Belongs to the EVI2A family.
Clinical Relevance
Disease Involvement
Proto-oncogene
Antibody