Protein detail
CD1B
T-cell surface glycoprotein CD1b (CD antigen CD1b)
Protein symbol CD1B | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count 1 | Protein classification CD markersPredicted membrane proteins |
Basic Information
Protein Names
T-cell surface glycoprotein CD1b (CD antigen CD1b)
Protein Class
CD markersPredicted membrane proteins
Protein Function
CD markers
Transmembrane
304..324; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CD1
Gene Description
CD1b molecule
Chromosome
1
Position
158327951-158331531
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBergmann gliaSingle-Nuclei Brain SpecificBergmann gliaBlood Cell SpecificbasophilBlood Lineage SpecificgranulocytesSecretome LocationSecreted - unknown locationSecretome FunctionReceptor
Function & Pathway
Protein Function
CD markers
Cellular Component
Molecular Function
Biological Process
Reactome
Canonical Pathways
M266 Pid ncadherin pathway
Mediation Categories
Fusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
38 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| cell_adhesion | cell_adhesion | Cellinker | Yes | Yes | No | Yes | No |
| adhesion | adhesion | OmniPath | Yes | Yes | No | Yes | No |
| cell_adhesion | cell_adhesion | OmniPath | Yes | Yes | No | Yes | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | Yes | No |
| transmembrane_predicted | transmembrane | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane | CellPhoneDB | No | No | No | Yes | No |
| transmembrane | transmembrane | TopDB | No | No | No | Yes | No |
| transmembrane | transmembrane | LOCATE | No | No | No | Yes | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation；Acoustic trapping | Mass spectrometry | 1 | 27487081 |
Sequence, Structure & Domains
Sequences
Length
333
Mass
36,939
Sequence
MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P29016-1; Sequence=Displayed; Name=2; IsoId=P29016-2; Sequence=VSP_016911
Alternative Sequence
242..296; Missing (in isoform 2)
3D Structural Models
Turn
60..63; 70..75; 103..107; 257..259
Helix
78..102; 153..155; 156..166; 172..181; 183..194; 196..199; 271..273; 284..286
Beta Strand
27..38; 41..50; 53..59; 64..67; 110..122; 128..136; 139..145; 148..151; 206..211; 219..232; 235..240; 248..250; 254..256; 260..270; 274..276; 277..282; 291..294
3D Structure
Electron microscopy (1); X-ray crystallography (23)
Domain & Motif Annotations
Motif
329..332; Internalization signal
Domain (FT)
185..295; Ig-like
Clinical Relevance
Antibody