Protein detail
CAP2
Adenylyl cyclase-associated protein 2 (CAP 2)
Protein symbol CAP2 | UniProt ID | EVMP score 0.50 |
Frequency 9 | Transmembrane count | Protein classification Cancer-related genesPredicted intracellular proteins |
Basic Information
Protein Names
Adenylyl cyclase-associated protein 2 (CAP 2)
Protein Class
Cancer-related genesPredicted intracellular proteins
Protein Function
- Cancer-related genes:Mutated cancer genes
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Description
Cyclase associated actin cytoskeleton regulatory protein 2
Chromosome
6
Position
17393595-17557780
Frequency
9
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificlymphoid tissueCell SpecificEsophageal apical cellsSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificclassical monocyteBlood Lineage Specificmonocytes
Function & Pathway
Protein Function
- Cancer-related genes:Mutated cancer genes
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
16 records.
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Sequence, Structure & Domains
Sequences
Length
477
Mass
52,824
Sequence
MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P40123-1; Sequence=Displayed; Name=2; IsoId=P40123-2; Sequence=VSP_055520; Name=3; IsoId=P40123-3; Sequence=VSP_055519
Alternative Sequence
75..334; Missing (in isoform 3); 149..212; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
230..246; Pro residues; 298..320; Low complexity
Domain (FT)
317..455; C-CAP/cofactor C-like
Region
225..261; Disordered; 274..321; Disordered
Protein Families
CAP family
Sequence Similarities
Belongs to the CAP family.