Protein detail
OX2G
OX-2 membrane glycoprotein (CD antigen CD200)
Protein symbol OX2G | UniProt ID | EVMP score 0.25 |
Frequency 3 | Transmembrane count 1 | Protein classification CD markersPredicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
OX-2 membrane glycoprotein (CD antigen CD200)
Protein Class
CD markersPredicted intracellular proteinsPredicted membrane proteins
Protein Function
- CD markers
- Predicted intracellular proteins
Transmembrane
233..259; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
MOX1MOX2MRCOX-2
Gene Description
CD200 molecule
Chromosome
3
Position
112332347-112362812
Frequency
3
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificbreastCell SpecificBreast hormone-responsive cellsSingle-Nuclei Brain Specificependymal cell
Function & Pathway
Protein Function
- CD markers
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Clinical-translation mediationFusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
37 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ligand | ligand | ICELLNET | Yes | No | No | Yes | No |
| ligand | ligand | CellTalkDB | Yes | No | No | Yes | No |
| ligand | ligand | LRdb | Yes | No | No | Yes | No |
| ligand | ligand | OmniPath | Yes | No | No | Yes | No |
| receptor | receptor | Cellinker | No | Yes | No | Yes | No |
| receptor | receptor | connectomeDB2020 | No | Yes | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Protein Organic Solvent Precipitation | Mass spectrometry | 1 | 32384937 |
Sequence, Structure & Domains
Sequences
Length
278
Mass
31,264
Sequence
MERLVIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGELSQGVQKMT
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P41217-1; Sequence=Displayed; Name=2; IsoId=P41217-2; Sequence=VSP_002613; Name=3; IsoId=P41217-3; Sequence=VSP_040027, VSP_002613
Alternative Sequence
4; L -> LTLTRTIGGPLLTATLLGKTTINDYQ (in isoform 3); 268..278; GELSQGVQKMT -> EP (in isoform 2 and isoform 3)
3D Structural Models
Domain & Motif Annotations
Domain (FT)
31..141; Ig-like V-type; 142..232; Ig-like C2-type
Clinical Relevance
Biomarker
Phase 2; Phase 1/2; Phase 1
Drugs
Antibody