Protein detail
MFAP3
Microfibril-associated glycoprotein 3
Protein symbol MFAP3 | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
Microfibril-associated glycoprotein 3
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
148..170; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Description
Microfibril associated protein 3
Chromosome
5
Position
154038959-154220478
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Cell SpecificBergmann gliaSingle-Nuclei Brain SpecificBergmann glia
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Fusion and delivery mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
23 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
2 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography | Mass spectrometry | 1 | 39120316 |
Sequence, Structure & Domains
Sequences
Length
362
Mass
40,165
Sequence
MKLHCCLFTLVASIIVPAAFVLEDVDFDQMVSLEANRSSYNASFPSSFELSASSHSDDDVIIAKEGTSVSIECLLTASHYEDVHWHNSKGQQLDGRSRGGKWLVSDNFLNITNVAFDDRGLYTCFVTSPIRASYSVTLRVIFTSGDMSVYYMIVCLIAFTITLILNVTRLCMMSSHLRKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLILNCRAFVEEMFEAVRVDDPDDLGERIKERPALNAQGGIYVINPEMGRSNSPGGDSDDGSLNEQGQEIAVQVSVHLQSETKSIDTESQGSSHFSPPDDIGSAESNCNYKDGAYENCQL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P55082-1; Sequence=Displayed; Name=2; IsoId=P55082-2; Sequence=VSP_042948
Alternative Sequence
1..146; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
323..337; Polar residues
Domain (FT)
45..137; Ig-like C2-type
Region
285..306; Disordered; 323..350; Disordered