Protein detail
CD69
Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)
Protein symbol CD69 | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count 1 | Protein classification CD markersPredicted membrane proteins |
Basic Information
Protein Names
Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)
Protein Class
CD markersPredicted membrane proteins
Protein Function
CD markers
Transmembrane
41..61; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CLEC2C
Gene Description
CD69 molecule
Chromosome
12
Position
9752486-9760901
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Cell SpecificAdipocytesSingle-Nuclei Brain Specificfibroblast
Function & Pathway
Protein Function
CD markers
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Adhesion and uptake mediationFusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
41 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| cell_surface_ligand | cell_surface_ligand | CellChatDB | Yes | No | No | No | No |
| cell_surface_ligand | cell_surface_ligand | OmniPath | Yes | No | No | No | No |
| cell_adhesion | cell_adhesion | Cellinker | Yes | Yes | No | No | No |
| adhesion | adhesion | OmniPath | Yes | Yes | No | No | No |
| cell_adhesion | cell_adhesion | OmniPath | Yes | Yes | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 36550367 |
Sequence, Structure & Domains
Sequences
Length
199
Mass
22,559
Sequence
MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIALSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTEVSSMECEKNLYWICNKPYK
3D Structural Models
Turn
115..117
Helix
106..114; 126..136
Beta Strand
90..92; 95..99; 141..147; 153..155; 168..170; 172..177; 180..184; 190..197
3D Structure
Electron microscopy (1); X-ray crystallography (5)
Domain & Motif Annotations
Domain (FT)
92..195; C-type lectin
Region
1..29; Disordered