Protein detail

CD69

Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)

Protein symbol
CD69
UniProt ID
EVMP score
0.25
Frequency
1
Transmembrane count
1
Protein classification
CD markersPredicted membrane proteins
Basic Information
Protein Names
Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)
Protein Class
CD markersPredicted membrane proteins
Protein Function
CD markers
Transmembrane
41..61; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
CLEC2C
Gene Description
CD69 molecule
Chromosome
12
Position
9752486-9760901
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Cell SpecificAdipocytesSingle-Nuclei Brain Specificfibroblast
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

41 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembraneUniProt_keywordNoNoNoNoNo
transmembrane_predictedtransmembraneOmniPathNoNoNoNoNo
transmembranetransmembraneGO_IntercellNoNoNoNoNo
transmembranetransmembraneTopDBNoNoNoNoNo
transmembranetransmembraneLOCATENoNoNoNoNo
transmembranetransmembraneRamilowski_locationNoNoNoNoNo
transmembranetransmembraneOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneCellinkerNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
CD69Q071082PDBPDB:1e8iPDB:3hupPDB:3cck

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry136550367
Sequence, Structure & Domains

Sequences

Length
199
Mass
22,559
Sequence
MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIALSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTEVSSMECEKNLYWICNKPYK

3D Structural Models

Turn
115..117
Helix
106..114; 126..136
Beta Strand
90..92; 95..99; 141..147; 153..155; 168..170; 172..177; 180..184; 190..197
3D Structure
Electron microscopy (1); X-ray crystallography (5)

Domain & Motif Annotations

Domain (FT)
92..195; C-type lectin
Region
1..29; Disordered
Clinical Relevance