Protein detail
IMPG1
Interphotoreceptor matrix proteoglycan 1 (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods)
Protein symbol IMPG1 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Disease related genesHuman disease related genesPredicted intracellular proteinsPredicted secreted proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Interphotoreceptor matrix proteoglycan 1 (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods)
Protein Class
Disease related genesHuman disease related genesPredicted intracellular proteinsPredicted secreted proteins
Protein Function
- Disease related genes
- Predicted secreted proteins
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
Ensembl
Entrez Gene Symbol
Gene Synonym
GP147IPM150SPACR
Gene Description
Interphotoreceptor matrix proteoglycan 1
Chromosome
6
Position
75921114-76072678
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificDistal convoluted tubule cellsSingle-Nuclei Brain Specificleukocyte
Function & Pathway
Protein Function
- Disease related genes
- Predicted secreted proteins
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
M185 Pid alk1 pathway
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
12 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| secreted | secreted | OmniPath | No | No | Yes | No | No |
| proteoglycan | ecm | Matrisome | Yes | No | Yes | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
797
Mass
89,387
Sequence
MYLETRRAIFVFWIFLQVQGTKDISINIYHSETKDIDNPPRNETTESTEKMYKMSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDWVSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPDRKDEISAEKTLGEPGETIVISTDVANVSLGPFPLTPDDTLLNEILDNTLNDTKMPTTERETEFAVLEEQRVELSVSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSSTEMQLTAIFKRHSAEAKSPASDLLSFDSNKIESEEVYHGTMEEDKQPEIYLTATDLKRLISKALEEEQSLDVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPELPPVEPQLETVDGAEHGLPDTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATDQTMLVPGLTIPTSDYSAISQLALGISHPPASSDDSRSSAGGEDMVRHLDEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTSSMTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQLEILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPADQADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQGSLDGLEPGLCGPGTKECEVLQGKGAPCRLPDHSENQAYKTSVKKFQNQQNNKVISKRNSELLTVEYEEFNHQDWEGN
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q17R60-1; Sequence=Displayed; Name=2; IsoId=Q17R60-2; Sequence=VSP_055981, VSP_055982, VSP_055983
Alternative Sequence
23..100; Missing (in isoform 2); 188..225; DVANVSLGPFPLTPDDTLLNEILDNTLNDTKMPTTERE -> EKNKGKTKPFNILQFGNNHHEHLLPIFCLLSSIIYTYY (in isoform 2); 226..797; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Motif
621..629; Heparin- and hyaluronan-binding
Domain (FT)
232..354; SEA 1; 571..684; SEA 2