Protein detail

ADCK5

Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)

Entry name
ADCK5
UniProt ID
Q3MIX3
EVMP confidence score
0.40
Supporting publications (n)
1
Transmembrane count
1
Protein classification
EnzymesPredicted membrane proteins
Basic Information
Protein Names
Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)
Protein Class (2)
EnzymesPredicted membrane proteins
Protein Function (2)
  • Enzymes
  • Kinases:Atypical kinases
Transmembrane
50..67; Helical
Transmembrane Count
1
Ensembl
ENSG00000173137
Entrez Gene Symbol
ADCK5
Gene Synonym
FLJ35454
Gene Description
AarF domain containing kinase 5
Chromosome
8
Position
144373101-144393242
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
ADCK5 fluorescence
Function & Pathway
Protein Function (2)
  • Enzymes
  • Kinases:Atypical kinases
Cellular Component (2)
Molecular Function (2)
Biological Process (3)
Canonical Pathways
M68 Pid rhoa reg pathway
Mediation Categories
Other mediation
Relations & Evidence18

Ligand-Receptor Signaling (11)

11 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathYes
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularOmniPath
transmembranetransmembraneUniProt_location
transmembranetransmembraneUniProt_topology
transmembranetransmembraneUniProt_keyword
transmembranetransmembraneRamilowski_location
transmembranetransmembraneOmniPath
receptorreceptorscConnectYes
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Regulatory Interaction Network (1)

1 record.

Source Protein SymbolSource UniProt IDTarget Protein SymbolTarget UniProt IDIs DirectedIs StimulationIs InhibitionDatabaseReferences
ADCK5Q3MIX3SOX9P48436YesYesSIGNOR_ProtMapperSIGNORPhosphoSite_ProtMapperProtMapperSIGNOR:32277958ProtMapper:32277958

Protein Complex Composition (5)

5 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
ADCK5JUNBOXSMRGPD3A6NKT7P17275Q3MIX3Q9NWU10:0:0:0hu.MAP
ADCK5BATF3FOSJUNBJUNDP01100P17275P17535Q3MIX3Q9NR550:0:0:0:0hu.MAP
ADCK5BATF3JUNBJUNDP17275P17535Q3MIX3Q9NR550:0:0:0hu.MAP
ADCK5ATF3BRCA1FOSBJUNBP17275P18847P38398P53539Q3MIX30:0:0:0:0hu.MAP2
ADCK5ATF3FOSBJUNBP17275P18847P53539Q3MIX30:0:0:0hu.MAP2

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyWestern BlottingMass Spectrometry136573687
Sequence, Structure & Domains

Sequences

Length
580
Mass
65,828
Sequence
MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET

Domain & Motif Annotations

Domain (FT)
179..419; Protein kinase
Protein Families (2)
  • Protein kinase superfamily
  • ADCK protein kinase family
Sequence Similarities
Belongs to the protein kinase superfamily. ADCK protein kinase family.
Clinical Relevance
Antibody (2)
HPA025692HPA028679
Supporting Publications1
PMIDTitleRelated sentences
38225453Deep proteomic analysis of obstetric antiphospholipid syndrome by DIA-MS of extracellular vesicle enriched fractions.No related sentences available