Protein detail
ADCK5
Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)
Protein symbol ADCK5 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification EnzymesPredicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)
Protein Class
EnzymesPredicted membrane proteins
Protein Function
- Enzymes
- Kinases:Atypical kinases
Transmembrane
50..67; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ35454
Gene Description
AarF domain containing kinase 5
Chromosome
8
Position
144373101-144393242
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Protein Function
- Enzymes
- Kinases:Atypical kinases
Cellular Component
Biological Process
Canonical Pathways
M68 Pid rhoa reg pathway
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
11 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
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Regulatory Interaction Network
1 record.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| ADCK5 | Q3MIX3 | SOX9 | P48436 | Yes | Yes | No | SIGNOR_ProtMapperSIGNORPhosphoSite_ProtMapperProtMapper | SIGNOR:32277958ProtMapper:32277958 |
Protein Complex Composition
5 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| ADCK5JUNBOXSMRGPD3 | A6NKT7P17275Q3MIX3Q9NWU1 | 0:0:0:0 | hu.MAP | |||
| ADCK5BATF3FOSJUNBJUND | P01100P17275P17535Q3MIX3Q9NR55 | 0:0:0:0:0 | hu.MAP | |||
| ADCK5BATF3JUNBJUND | P17275P17535Q3MIX3Q9NR55 | 0:0:0:0 | hu.MAP | |||
| ADCK5ATF3BRCA1FOSBJUNB | P17275P18847P38398P53539Q3MIX3 | 0:0:0:0:0 | hu.MAP2 | |||
| ADCK5ATF3FOSBJUNB | P17275P18847P53539Q3MIX3 | 0:0:0:0 | hu.MAP2 |
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western BlottingMass Spectrometry | 1 | 36573687 |
Sequence, Structure & Domains
Sequences
Length
580
Mass
65,828
Sequence
MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
3D Structural Models
Domain & Motif Annotations
Domain (FT)
179..419; Protein kinase
Protein Families
- Protein kinase superfamily
- ADCK protein kinase family
Sequence Similarities
Belongs to the protein kinase superfamily. ADCK protein kinase family.