Protein detail
T4S20
Transmembrane 4 L6 family member 20
Entry name T4S20 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 4 | Protein classification Disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransporters |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Transmembrane 4 L6 family member 20
Protein Class
Disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransporters
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Transporters:Accessory Factors Involved in Transport
- Potential drug targets
Transmembrane
15..35; Helical; 45..65; Helical; 84..104; Helical; 186..206; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ22800TCCE518
Gene Description
Transmembrane 4 L six family member 20
Chromosome
2
Position
227362038-227381995
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificAdipocytesBlood Cell Specificmemory CD8 T-cellBlood Lineage SpecificT-cells
Function & Pathway
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Transporters:Accessory Factors Involved in Transport
- Potential drug targets
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
- M273 Pid epha2 fwd pathway
- M268 Pid s1p s1p2 pathway
- M76 Pid p38 alpha beta pathway
Mediation Categories
Adhesion and uptake mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
11 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
Sequence, Structure & Domains
Sequences
Length
229
Mass
25,075
Sequence
MTCCEGWTSCNGFSLLVLLLLGVVLNAIPLIVSLVEEDQFSQNPISCFEWWFPGIIGAGLMAIPATTMSLTARKRACCNNRTGMFLSSLFSVITVIGALYCMLISIQALLKGPLMCNSPSNSNANCEFSLKNISDIHPESFNLQWFFNDSCAPPTGFNKPTSNDTMASGWRASSFHFDSEENKHRLIHFSVFLGLLLVGILEVLFGLSQIVIGFLGCLCGVSKRRSQIV
3D Structural Models
Domain & Motif Annotations
Domain (CC)
The first transmembrane helix plays a critical role for the insertion orientation in the endoplasmic reticulum membrane.
Protein Families
L6 tetraspanin family
Sequence Similarities
Belongs to the L6 tetraspanin family.