Protein detail
NTCP5
Sodium/bile acid cotransporter 5 (Na(+)/bile acid cotransporter 5) (Solute carrier family 10 member 5)
Entry name NTCP5 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count 9 | Protein classification Predicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Sodium/bile acid cotransporter 5 (Na(+)/bile acid cotransporter 5) (Solute carrier family 10 member 5)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Electrochemical Potential-driven transporters
Transmembrane
143..163; Helical; 175..195; Helical; 207..227; Helical; 232..252; Helical; 271..291; Helical; 309..329; Helical; 334..354; Helical; 368..388; Helical; 398..418; Helical
Transmembrane Count
9
Ensembl
Entrez Gene Symbol
Gene Description
Solute carrier family 10 member 5
Chromosome
8
Position
81693631-81695058
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Cell SpecificAlveolar cells type 1Single-Nuclei Brain Specificastrocyte
Function & Pathway
Protein Function
Transporters:Electrochemical Potential-driven transporters
Cellular Component
Molecular Function
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence16
Ligand-Receptor Signaling (15)
15 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | Yes | ||||
| transporter | transporter | Surfaceome | Yes | ||||
| solute_carrier | transporter | Almen2009 | Yes | ||||
| slc10 | transporter | Surfaceome | Yes | ||||
| slc | transporter | Surfaceome | Yes | ||||
| transporter | transporter | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location |
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Sequence, Structure & Domains
Sequences
Length
438
Mass
48,871
Sequence
MIRKLFIVLLLLLVTIEEARMSSLSFLNIEKTEILFFTKTEETILVSSSYENKRPNSSHLFVKIEDPKILQMVNVAKKISSDATNFTINLVTDEEGETNVTIQLWDSEGRQERLIEEIKNVKVKVLKQKDSLLQAPMHIDRNILMLILPLILLNKCAFGCKIELQLFQTVWKRPLPVILGAVTQFFLMPFCGFLLSQIVALPEAQAFGVVMTCTCPGGGGGYLFALLLDGDFTLAILMTCTSTLLALIMMPVNSYIYSRILGLSGTFHIPVSKIVSTLLFILVPVSIGIVIKHRIPEKASFLERIIRPLSFILMFVGIYLTFTVGLVFLKTDNLEVILLGLLVPALGLLFGYSFAKVCTLPLPVCKTVAIESGMLNSFLALAVIQLSFPQSKANLASVAPFTVAMCSGCEMLLIILVYKAKKRCIFFLQDKRKRNFLI
Domain & Motif Annotations
Protein Families
Bile acid:sodium symporter (BASS) (TC 2.A.28) family
Sequence Similarities
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 27894104 | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. | No related sentences available |