Protein detail

CBPZ

Carboxypeptidase Z (CPZ) (EC 3.4.17.-)

Protein symbol
CBPZ
UniProt ID
EVMP score
0.60
Frequency
14
Transmembrane count
Protein classification
Basic Information
Protein Names
Carboxypeptidase Z (CPZ) (EC 3.4.17.-)
Protein Function
  • Peptidases:Metallopeptidases
  • Enzymes
  • Predicted secreted proteins
  • Predicted intracellular proteins
Entrez Gene Symbol
Frequency
14
EVMP Score
0.60
Fluorescence & Localization
Function & Pathway
Protein Function
  • Peptidases:Metallopeptidases
  • Enzymes
  • Predicted secreted proteins
  • Predicted intracellular proteins
Mediation Categories
Metabolism mediationReceptor-signaling mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

18 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathNoYesYesNoNo
m14_carboxypeptidasesecreted_peptidaseOmniPathNoNoYesNoNo
carboxypeptidasesecreted_peptidaseOmniPathNoNoYesNoNo
secreted_enzymesecreted_enzymeOmniPathYesNoYesNoNo
ecmecmMatrixDBYesNoYesNoNo
ecmecmUniProt_locationYesNoYesNoNo
ecmecmCellCellInteractionsYesNoYesNoNo
ecmecmOmniPathYesNoYesNoNo
extracellularextracellularLOCATENoNoYesNoNo
extracellularextracellularOmniPathNoNoYesNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyWestern blottingELISA432795414387318682680191940784529
Sequence, Structure & Domains

Sequences

Length
652
Mass
73,655
Sequence
MPPPLPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q66K79-1; Sequence=Displayed; Name=2; IsoId=Q66K79-2; Sequence=VSP_020983; Name=3; IsoId=Q66K79-3; Sequence=VSP_040356
Alternative Sequence
1..137; Missing (in isoform 3); 30..40; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Domain (FT)
27..160; FZ; 186..502; Peptidase M14
Region
595..629; Disordered
Protein Families
Peptidase M14 family
Sequence Similarities
Belongs to the peptidase M14 family.
Clinical Relevance