Protein detail
TMC5A
Transmembrane and coiled-coil domain-containing protein 5A
Protein symbol TMC5A | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Transmembrane and coiled-coil domain-containing protein 5A
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
224..244; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
MGC35118TMCO5
Gene Description
Transmembrane and coiled-coil domains 5A
Chromosome
15
Position
37921939-37967724
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
14 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | No | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | No | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
288
Mass
34,174
Sequence
MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLSYMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8N6Q1-1; Sequence=Displayed; Name=2; IsoId=Q8N6Q1-2; Sequence=VSP_028246, VSP_028247
Alternative Sequence
224..228; IFCCL -> WASSF (in isoform 2); 229..288; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Coiled Coil
10..192
Protein Families
TMCO5 family
Sequence Similarities
Belongs to the TMCO5 family.