Protein detail

S43A3

Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)

Entry name
S43A3
UniProt ID
Q8NBI5
EVMP confidence score
0.60
Supporting publications (n)
13
Transmembrane count
12
Protein classification
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Basic Information
Protein Names
Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)
Protein Class (3)
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Protein Function (2)
  • Transporters:Electrochemical Potential-driven transporters
  • Predicted intracellular proteins
Transmembrane
17..37; Helical; 72..92; Helical; 102..122; Helical; 123..143; Helical; 156..176; Helical; 188..208; Helical; 279..299; Helical; 319..339; Helical; 356..376; Helical; 396..418; Helical; 427..447; Helical; 456..476; Helical
Transmembrane Count
12
Ensembl
ENSG00000134802
Entrez Gene Symbol
SLC43A3
Gene Synonym (5)
DKFZp762A227Eeg1FOAP-13PRO1659SEEEG-1
Gene Description
Solute carrier family 43 member 3
Chromosome
11
Position
57406954-57427580
Supporting publications (n)
13
EVMP confidence score
0.60
Function & Pathway
Protein Function (2)
  • Transporters:Electrochemical Potential-driven transporters
  • Predicted intracellular proteins
Cellular Component
GO:0016323 basolateral plasma membrane
Molecular Function (5)
Mediation Categories (2)
Clinical-translation mediationFusion and delivery mediation
Relations & Evidence22

Ligand-Receptor Signaling (21)

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembrane_predictedPhobius
Page 3 of 3Previous

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryWestern blotting431508500337095103792230033709510
Sequence, Structure & Domains

Sequences

Length
491
Mass
54,529
Sequence
MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQADCKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFISVCSTWHVARTFLLMPRGHIPYPLPPNYSYGLCPGNGTTKEEKETAEHENRELQSKEFLSAKEETPGAGQKQELRSFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMARVSTYTNAFAFTQFGVLCAPWNGLLMDRLKQKYQKEARKTGSSTLAVALCSTVPSLALTSLLCLGFALCASVPILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLAILLTFFHPFLVYRECRTWKESPSAIA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NBI5-1; Sequence=Displayed; Name=2; IsoId=Q8NBI5-2; Sequence=VSP_055620
Alternative Sequence
61; A -> AGRLGCMGDLFSTP (in isoform 2)

Domain & Motif Annotations

Protein Families
SLC43A transporter (TC 2.A.1.44) family
Sequence Similarities
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
Clinical Relevance
Antibody (2)
HPA030551HPA077244
Interaction Protein
ENSG00000165280
Interaction Count
1
Interaction Dataset
intact_biogrid
Supporting Publications13
PMIDTitleRelated sentences
27863537High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.No related sentences available
27894104Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.No related sentences available
28986585Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.No related sentences available
30408591Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.No related sentences available
30950185Unique Protein Profiles of Extracellular Vesicles as Diagnostic Biomarkers for Early and Advanced Non-Small Cell Lung Cancer.No related sentences available
33204424Proteomic analysis of extracellular vesicles reveals an immunogenic cargo in rheumatoid arthritis synovial fluid.No related sentences available
33709510Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection.No related sentences available
34186243A Reductionist Approach Using Primary and Metastatic Cell-Derived Extracellular Vesicles Reveals Hub Proteins Associated with Oral Cancer Prognosis.No related sentences available
34817906Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform.No related sentences available
37205098Proteomic profiling of extracellular vesicles in synovial fluid and plasma from Oligoarticular Juvenile Idiopathic Arthritis patients reveals novel immunopathogenic biomarkers.No related sentences available
Page 1 of 2Next