Protein detail

STML3

Stomatin-like protein 3 (SLP-3)

Protein symbol
STML3
UniProt ID
EVMP score
0.72
Frequency
12
Transmembrane count
1
Protein classification
Predicted membrane proteinsTransporters
Basic Information
Protein Names
Stomatin-like protein 3 (SLP-3)
Protein Class
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
29..49; Helical; Signal-anchor for type III membrane protein
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
Epb7.2lSRO
Gene Description
Stomatin like 3
Chromosome
13
Position
38965925-38990859
Frequency
12
EVMP Score
0.72
Fluorescence & Localization
Cell SpecificAstrocytesSingle-Nuclei Brain SpecificBergmann glia
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

19 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoYesNo
intracellularintracellularOmniPathNoNoNoYesNo
ion_channelion_channelDGIdbNoYesNoYesNo
transportertransporterOmniPathNoYesNoYesNo
ion_channelion_channelOmniPathNoYesNoYesNo
transmembranetransmembraneUniProt_locationNoNoNoYesNo
transmembranetransmembraneUniProt_topologyNoNoNoYesNo
transmembranetransmembraneUniProt_keywordNoNoNoYesNo
transmembrane_predictedtransmembraneOmniPathNoNoNoYesNo
transmembranetransmembraneLOCATENoNoNoYesNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometryELISA437322475410682533359250041307968
Sequence, Structure & Domains

Sequences

Length
291
Mass
32,135
Sequence
MDSRVSSPEKQDKENFVGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPMNILEGIGGVSYDNHKKLPNKA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TAV4-1; Sequence=Displayed; Name=2; IsoId=Q8TAV4-2; Sequence=VSP_042937
Alternative Sequence
1..16; MDSRVSSPEKQDKENF -> MNSRGEL (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families
Band 7/mec-2 family
Sequence Similarities
Belongs to the band 7/mec-2 family.
Clinical Relevance