Protein detail
STML3
Stomatin-like protein 3 (SLP-3)
Entry name STML3 | UniProt ID | EVMP confidence score 0.72 |
Supporting publications (n) 12 | Transmembrane count 1 | Protein classification Predicted membrane proteinsTransporters |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information13
Protein Names
Stomatin-like protein 3 (SLP-3)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
29..49; Helical; Signal-anchor for type III membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
Epb7.2lSRO
Gene Description
Stomatin like 3
Chromosome
13
Position
38965925-38990859
Supporting publications (n)
12
EVMP confidence score
0.72
Fluorescence & Localization2
Cell SpecificAstrocytesSingle-Nuclei Brain SpecificBergmann glia
Function & Pathway6
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component (5)
Molecular Function (2)
Biological Process (3)
Reactome (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence20
Ligand-Receptor Signaling (19)
19 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | Yes | No |
| intracellular | intracellular | OmniPath | No | No | No | Yes | No |
| ion_channel | ion_channel | DGIdb | No | Yes | No | Yes | No |
| transporter | transporter | OmniPath | No | Yes | No | Yes | No |
| ion_channel | ion_channel | OmniPath | No | Yes | No | Yes | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | Yes | No |
| transmembrane_predicted | transmembrane | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane | LOCATE | No | No | No | Yes | No |
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Sequence, Structure & Domains7
Sequences
Length
291
Mass
32,135
Sequence
MDSRVSSPEKQDKENFVGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPMNILEGIGGVSYDNHKKLPNKA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TAV4-1; Sequence=Displayed; Name=2; IsoId=Q8TAV4-2; Sequence=VSP_042937
Alternative Sequence
1..16; MDSRVSSPEKQDKENF -> MNSRGEL (in isoform 2)
Domain & Motif Annotations
Protein Families
Band 7/mec-2 family
Sequence Similarities
Belongs to the band 7/mec-2 family.
Supporting Publications12
| PMID | Title | Abstract |
|---|---|---|
| 39290459 | Urinary extracellular vesicles as a monitoring tool for renal damage in patients not meeting criteria for chronic kidney disease. | No abstract available |
| 40091455 | Potential Role of Menstrual Fluid-Derived Small Extracellular Vesicle Proteins in Endometriosis Pathogenesiss. | No abstract available |
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