Protein detail
C99L2
CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99)
Protein symbol C99L2 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins |
Basic Information
Protein Names
CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99)
Protein Class
Predicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins
Protein Function
- Predicted secreted proteins
- Predicted intracellular proteins
Transmembrane
186..206; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CD99BMIC2L1
Gene Description
CD99 molecule like 2
Chromosome
X
Position
150766336-150898816
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificadipose tissueCell SpecificEpicardial cellsBlood Cell SpecificeosinophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function
- Predicted secreted proteins
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
KEGG
Mediation Categories
Adhesion and uptake mediationFusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
25 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| secreted | secreted | OmniPath | No | No | Yes | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | Yes | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | Yes | Yes | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | Yes | Yes | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | Yes | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
4 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| CAPN1CAPNS1CAPNS2CASTCD99L2TRIP12 | P04632P07384P20810Q14669Q8TCZ2Q96L46 | 0:0:0:0:0:0 | hu.MAP2 | |||
| CAPN1CAPNS1CD99L2RP9TRIP12 | P04632P07384Q14669Q8TA86Q8TCZ2 | 0:0:0:0:0 | hu.MAP2 | |||
| CAPN1CAPNS1CD99L2 | P04632P07384Q8TCZ2 | 0:0:0 | hu.MAP2 | |||
| BHLHE41CD99L2 | Q8TCZ2Q9C0J9 | 0:0 | hu.MAP |
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | 1 | 27086912 |
Sequence, Structure & Domains
Sequences
Length
262
Mass
27,986
Sequence
MVAWRSAFLVCLAFSLATLVQRGSGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI
Alternative Products
Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q8TCZ2-1; Sequence=Displayed; Name=2; IsoId=Q8TCZ2-2; Sequence=VSP_034184; Name=3; IsoId=Q8TCZ2-3; Sequence=VSP_034182, VSP_034183; Name=4; IsoId=Q8TCZ2-4; Sequence=VSP_034181, VSP_034185; Name=5; IsoId=Q8TCZ2-5; Sequence=VSP_041815, VSP_041816; Name=6; IsoId=Q8TCZ2-6; Sequence=VSP_044663
Alternative Sequence
44..145; QPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGF -> PALGMYHKLDGLKQQNFILSLFWMLEVLYQGVGWATFSLKALGKNLSLTFPTSGGSRCSLVCGCITPISASVVTWCSPFCVSLLSLTKMLVSGFKAHLDNPG (in isoform 4); 44; Q -> R (in isoform 3); 45..116; Missing (in isoform 3); 45..93; Missing (in isoform 2); 68; G -> GPTEG (in isoform 5); 93..165; Missing (in isoform 6); 146..262; Missing (in isoform 4); 218..219; QQ -> QHAAAGQE (in isoform 5)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
49..60; Low complexity; 98..119; Low complexity; 125..136; Basic and acidic residues; 159..168; Basic and acidic residues
Region
38..181; Disordered
Protein Families
CD99 family
Sequence Similarities
Belongs to the CD99 family.