Protein detail
MO2R1
Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1)
Entry name MO2R1 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1)
Protein Function
Predicted intracellular proteins
Transmembrane
266..286; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAstrocytesBlood Cell SpecificbasophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Canonical Pathways
- M184 Pid ecadherin keratinocyte pathway
- M72 Pid nectin pathway
- M266 Pid ncadherin pathway
Mediation Categories
Fusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
45 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | CellPhoneDB | No | Yes | Yes | Yes | No |
| receptor | receptor | GO_Intercell | No | Yes | Yes | Yes | No |
| receptor | receptor | ICELLNET | No | Yes | Yes | Yes | No |
| receptor | receptor | CellChatDB | No | Yes | Yes | Yes | No |
| receptor | receptor | CellTalkDB | No | Yes | Yes | Yes | No |
| receptor | receptor | Surfaceome | No | Yes | Yes | Yes | No |
| receptor | receptor | LRdb | No | Yes | Yes | Yes | No |
| ig | receptor | Surfaceome | No | Yes | Yes | Yes | No |
| receptor | receptor | OmniPath | No | Yes | Yes | Yes | No |
| ecm | ecm | MatrixDB | Yes | No | Yes | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyPolymer PrecipitationImmunoaffinity Capture | Mass spectrometry | 15 | 268265363811336840465195353599233649718434064677401894973285431540985879375638574130796836146834318059583820710639207047 |
Sequence, Structure & Domains
Sequences
Length
348
Mass
39,041
Sequence
MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=4; IsoId=Q8TD46-4; Sequence=Displayed; Name=1; IsoId=Q8TD46-1; Sequence=VSP_061888; Name=2; IsoId=Q8TD46-2; Sequence=VSP_061889, VSP_061890; Name=3; IsoId=Q8TD46-3; Sequence=VSP_061888, VSP_061889, VSP_061890
Alternative Sequence
22..45; AEAEGAAQPNNSLMLQTSKENHAL -> A (in isoform 1 and isoform 3); 174..188; VTPEVTLFQNRNRTA -> GKEHHILRYFTSPDL (in isoform 2 and isoform 3); 189..348; Missing (in isoform 2 and isoform 3)
3D Structural Models
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Domain (FT)
160..251; Ig-like C2-type
Protein Families
CD200R family
Sequence Similarities
Belongs to the CD200R family.