Protein detail

PAQR8

Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)

Entry name
PAQR8
UniProt ID
Q8TEZ7
EVMP confidence score
0.40
Supporting publications (n)
1
Transmembrane count
7
Protein classification
Basic Information
Protein Names
Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)
Protein Function
Transporters:Transporter channels and pores
Transmembrane
76..96; Helical; Name=1; 112..132; Helical; Name=2; 175..195; Helical; Name=3; 214..234; Helical; Name=4; 244..264; Helical; Name=5; 284..304; Helical; Name=6; 320..340; Helical; Name=7
Transmembrane Count
7
Ensembl
ENSG00000170915
Entrez Gene Symbol
PAQR8
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
PAQR8 fluorescence
Secretome LocationIntracellular and membraneSecretome FunctionOther
Function & Pathway
Protein Function
Transporters:Transporter channels and pores
Cellular Component (2)
Molecular Function (3)
Biological Process (3)
KEGG
hsa05207 Chemical carcinogenesis - receptor activation
Canonical Pathways (3)
  • M5880 Naba ecm affiliated
  • M5885 Naba matrisome associated
  • M5889 Naba matrisome
Mediation Categories
Other mediation
Relations & Evidence17

Ligand-Receptor Signaling (16)

16 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathYes
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularOmniPath
transmembranetransmembraneUniProt_location
transmembranetransmembraneUniProt_topology
transmembranetransmembraneUniProt_keyword
transmembranetransmembraneLOCATE
transmembranetransmembraneRamilowski_location
transmembranetransmembraneOmniPath
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Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry；Western blotting；ELISA；Immunoelectron Microscopy23955813439940923
Sequence, Structure & Domains

Sequences

Length
354
Mass
40,464
Sequence
MTTAILERLSTLSVSGQQLRRLPKILEDGLPKMPCTVPETDVPQLFREPYIRTGYRPTGHEWRYYFFSLFQKHNEVVNVWTHLLAALAVLLRFWAFAEAEALPWASTHSLPLLLFILSSITYLTCSLLAHLLQSKSELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYDRFWLFFLPAAAFCGWLSCAGCCYAKYRYRRPYPVMRKICQVVPAGLAFILDISPVAHRVALCHLAGCQEQAAWYHTLQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFLSICTLSQLEAILLDYQGRQEIFLQRHGPLSVHMACLSFFFLAACSAATAALLRHKVKARLTKKDS

Domain & Motif Annotations

Protein Families
ADIPOR family
Sequence Similarities
Belongs to the ADIPOR family.
Supporting Publications1
PMIDTitleRelated sentences
38716512Assessment of urine sample collection and processing variables for extracellular vesicle-based proteomics.No related sentences available