Protein detail

PAQR8

Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)

Entry name
PAQR8
UniProt ID
EVMP score
0.50
Frequency
1
Transmembrane count
7
Protein classification
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)
Protein Function
Transporters:Transporter channels and pores
Transmembrane
76..96; Helical; Name=1; 112..132; Helical; Name=2; 175..195; Helical; Name=3; 214..234; Helical; Name=4; 244..264; Helical; Name=5; 284..304; Helical; Name=6; 320..340; Helical; Name=7
Transmembrane Count
7
Entrez Gene Symbol
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
PAQR8 fluorescence
Secretome LocationIntracellular and membraneSecretome FunctionOther
Function & Pathway
Protein Function
Transporters:Transporter channels and pores
Canonical Pathways
  • M5880 Naba ecm affiliated
  • M5885 Naba matrisome associated
  • M5889 Naba matrisome
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

16 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathNoYesNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo
transmembranetransmembraneUniProt_locationNoNoNoNoNo
transmembranetransmembraneUniProt_topologyNoNoNoNoNo
transmembranetransmembraneUniProt_keywordNoNoNoNoNo
transmembranetransmembraneLOCATENoNoNoNoNo
transmembranetransmembraneRamilowski_locationNoNoNoNoNo
transmembranetransmembraneOmniPathNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry;Western blotting;ELISA;Immunoelectron Microscopy23955813439940923
Sequence, Structure & Domains

Sequences

Length
354
Mass
40,464
Sequence
MTTAILERLSTLSVSGQQLRRLPKILEDGLPKMPCTVPETDVPQLFREPYIRTGYRPTGHEWRYYFFSLFQKHNEVVNVWTHLLAALAVLLRFWAFAEAEALPWASTHSLPLLLFILSSITYLTCSLLAHLLQSKSELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYDRFWLFFLPAAAFCGWLSCAGCCYAKYRYRRPYPVMRKICQVVPAGLAFILDISPVAHRVALCHLAGCQEQAAWYHTLQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFLSICTLSQLEAILLDYQGRQEIFLQRHGPLSVHMACLSFFFLAACSAATAALLRHKVKARLTKKDS

3D Structural Models

Domain & Motif Annotations

Protein Families
ADIPOR family
Sequence Similarities
Belongs to the ADIPOR family.
Clinical Relevance