Protein detail

AGRG7

Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128)

Protein symbol AGRG7	UniProt ID Q96K78	EVMP score 0.50
Frequency 1	Transmembrane count 7	Protein classification

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128)

Protein Function

G-protein coupled receptors:Family 2 (B) receptors
G-protein coupled receptors:GPCRs excl olfactory receptors

Transmembrane

439..459; Helical; Name=1; 469..489; Helical; Name=2; 529..549; Helical; Name=3; 566..586; Helical; Name=4; 624..644; Helical; Name=5; 670..690; Helical; Name=6; 699..719; Helical; Name=7

Transmembrane Count

Ensembl

ENSG00000144820

Entrez Gene Symbol

ADGRG7

Frequency

EVMP Score

0.50

Fluorescence & Localization

Function & Pathway

Protein Function

G-protein coupled receptors:Family 2 (B) receptors
G-protein coupled receptors:GPCRs excl olfactory receptors

Cellular Component

Molecular Function

Biological Process

Mediation Categories

Receptor-signaling mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

37 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
receptor	receptor	HPMR	No	Yes	No	Yes	No
receptor	receptor	Surfaceome	No	Yes	No	Yes	No
gpcr	receptor	DGIdb	No	Yes	No	Yes	No
gpcr	receptor	Almen2009	No	Yes	No	Yes	No
gpcr	receptor	UniProt_keyword	No	Yes	No	Yes	No
seven_transmembrane_7tm	receptor	HPMR	No	Yes	No	Yes	No
7tm_b	receptor	HPMR	No	Yes	No	Yes	No
7tm_type_b_polypeptide_7tm_b	receptor	HPMR	No	Yes	No	Yes	No
gpcr	receptor	Surfaceome	No	Yes	No	Yes	No
adhesion	receptor	Surfaceome	No	Yes	No	Yes	No

Page 1 of 4Next

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometry\|Western blottingMass spectrometry	2	37027237 37268950

Sequence, Structure & Domains

Sequences

Length

797

Mass

88,909

Sequence

MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWENGRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRLCSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSPSTEEITLSESDNAKESI

3D Structural Models

Domain & Motif Annotations

Domain (FT)

275..428; GAIN-B

Region

383..428; GPS

Protein Families

G-protein coupled receptor 2 family
Adhesion G-protein coupled receptor (ADGR) subfamily

Sequence Similarities

Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.

Clinical Relevance

Drugs

CAPECITABINE