Protein detail
AGRG7
Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128)
Entry name AGRG7 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count 7 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128)
Protein Function (2)
- G-protein coupled receptors:Family 2 (B) receptors
- G-protein coupled receptors:GPCRs excl olfactory receptors
Transmembrane
439..459; Helical; Name=1; 469..489; Helical; Name=2; 529..549; Helical; Name=3; 566..586; Helical; Name=4; 624..644; Helical; Name=5; 670..690; Helical; Name=6; 699..719; Helical; Name=7
Transmembrane Count
7
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.53
Function & Pathway
Protein Function (2)
- G-protein coupled receptors:Family 2 (B) receptors
- G-protein coupled receptors:GPCRs excl olfactory receptors
Cellular Component (2)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence38
Ligand-Receptor Signaling (37)
37 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| class_b2_adhesion | receptor | GPCRdb | Yes | Yes | |||
| class_b2_adhesion_adhesion | receptor | GPCRdb | Yes | Yes | |||
| class_b2_adhesion_adhesion_adgrg | receptor | GPCRdb | Yes | Yes | |||
| receptor | receptor | OmniPath | Yes | Yes | |||
| extracellular | extracellular | HPMR | Yes | ||||
| extracellular | extracellular | OmniPath | Yes | ||||
| adhesion_gprotein_coupled_receptor | matrix_adhesion | HGNC | Yes | Yes | |||
| adhesion | adhesion | HGNC | Yes | Yes | Yes | ||
| adhesion | adhesion | Almen2009 | Yes | Yes | Yes | ||
| matrix_adhesion | matrix_adhesion | HGNC | Yes | Yes |
Sequence, Structure & Domains
Sequences
Length
797
Mass
88,909
Sequence
MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWENGRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRLCSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSPSTEEITLSESDNAKESI
Domain & Motif Annotations
Domain (FT)
275..428; GAIN-B
Region
383..428; GPS
Protein Families (2)
- G-protein coupled receptor 2 family
- Adhesion G-protein coupled receptor (ADGR) subfamily
Sequence Similarities
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Clinical Relevance
Drugs
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 31805958 | Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment. | No related sentences available |