Protein detail
APLD1
Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein)
Protein symbol APLD1 | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count 3 | Protein classification Predicted membrane proteins |
Basic Information
Protein Names
Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein)
Protein Class
Predicted membrane proteins
Transmembrane
83..105; Helical; 122..142; Helical; 192..212; Helical
Transmembrane Count
3
Ensembl
Entrez Gene Symbol
Gene Synonym
DKFZP434F0318FLJ25138
Gene Description
Apolipoprotein L domain containing 1
Chromosome
12
Position
12725917-12829975
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificbrainCell SpecificEsophageal apical cellsBlood Cell Specificmemory B-cellBlood Lineage SpecificB-cells
Function & Pathway
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
15 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | No | No | No | No |
| ecm | ecm | OmniPath | Yes | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | LOCATE | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationMicrofluidics-Based Methods | Mass spectrometry | 1 | 41167904 |
Sequence, Structure & Domains
Sequences
Length
279
Mass
30,546
Sequence
MFRAPCHRLRARGTRKARAGAWRGCTFPCLGKGMERPAAREPHGPDALRRFQGLLLDRRGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSAVGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMREILSCLEFFCRWQGCGDRQLLQCGRNASIALYNSVYFIVFFGSRGFLIPRRAEGDTKVSQAVLKAKIQKLAESLESCTGALDELSEQLESRVQLCTKSSRGHDLKISADQRAGLFF
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96LR9-1; Sequence=Displayed; Name=2; IsoId=Q96LR9-2; Sequence=VSP_019960
Alternative Sequence
2..32; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Coiled Coil
226..253
Protein Families
Apolipoprotein L family
Sequence Similarities
Belongs to the apolipoprotein L family.