Protein detail
SERC2
Serine incorporator 2 (Tumor differentially expressed protein 2-like)
Protein symbol SERC2 | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count 11 | Protein classification Predicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Serine incorporator 2 (Tumor differentially expressed protein 2-like)
Protein Class
Predicted membrane proteins
Transmembrane
5..27; Helical; 40..57; Helical; 96..118; Helical; 131..150; Helical; 160..182; Helical; 202..224; Helical; 239..256; Helical; 268..290; Helical; 317..339; Helical; 385..407; Helical; 422..444; Helical
Transmembrane Count
11
Ensembl
Entrez Gene Symbol
Gene Synonym
FKSG84PRO0899TDE2TDE2L
Gene Description
Serine incorporator 2
Chromosome
1
Position
31409565-31434680
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificadrenal glandCell SpecificAdrenal cortex cells
Function & Pathway
Cellular Component
Biological Process
Mediation Categories
Metabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
13 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transporter | transporter | Surfaceome | No | Yes | No | No | No |
| serinc | transporter | Surfaceome | No | Yes | No | No | No |
| transporter | transporter | OmniPath | No | Yes | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Page 1 of 2Next
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | Mass spectrometryWestern blotting | 1 | 34265469 |
Sequence, Structure & Domains
Sequences
Length
455
Mass
50,742
Sequence
MGACLGACSLLSCASCLCGSAPCILCSCCPASRNSTVSRLIFTFFLFLGVLVSIIMLSPGVESQLYKLPWVCEEGAGIPTVLQGHIDCGSLLGYRAVYRMCFATAAFFFFFTLLMLCVSSSRDPRAAIQNGFWFFKFLILVGLTVGAFYIPDGSFTNIWFYFGVVGSFLFILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTEPSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPEQKCNPHLPTQLGNETVVAGPEGYETQWWDAPSIVGLIIFLLCTLFISLRSSDHRQVNSLMQTEECPPMLDATQQQQQVAACEGRAFDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYKPGETRKMISTWTAVWVKICASWAGLLLYLWTLVAPLLLRNRDFS
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q96SA4-1; Sequence=Displayed; Name=2; IsoId=Q96SA4-2; Sequence=VSP_042464; Name=3; IsoId=Q96SA4-3; Sequence=VSP_042463; Name=4; IsoId=Q96SA4-4; Sequence=VSP_046840
Alternative Sequence
1..13; MGACLGACSLLSC -> MRSMRLREEESPGPSHT (in isoform 3); 1..13; MGACLGACSLLSC -> MDGRMMRSMRLREEESPGPSHT (in isoform 4); 4..13; CLGACSLLSC -> EGAPDFLSCPRVRR (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Protein Families
TDE1 family
Sequence Similarities
Belongs to the TDE1 family.
Clinical Relevance
Antibody