Protein detail

S10AE

Protein S100-A14 (S100 calcium-binding protein A14) (S114)

Protein symbol S10AE	UniProt ID Q9HCY8	EVMP score 0.60
Frequency 18	Transmembrane count	Protein classification Plasma proteinsPredicted intracellular proteins

Basic Information

Protein Names

Protein S100-A14 (S100 calcium-binding protein A14) (S114)

Protein Class

Plasma proteinsPredicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000189334

Entrez Gene Symbol

S100A14

Gene Synonym

BCMP84S100A15

Gene Description

S100 calcium binding protein A14

Chromosome

Position

153614255-153616986

Frequency

EVMP Score

0.60

Fluorescence & Localization

Cell SpecificEnterocytes

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

Biological Process

KEGG

hsa04382 Cornified envelope formation

Mediation Categories

Immune mediationMetabolism mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

10 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
extracellular	extracellular	OmniPath	No	No	Yes	No	No
intracellular	intracellular	LOCATE	No	No	Yes	No	No
intracellular	intracellular	ComPPI	No	No	Yes	No	No
intracellular	intracellular	GO_Intercell	No	No	Yes	No	No
intracellular	intracellular	UniProt_location	No	No	Yes	No	No
intracellular	intracellular	OmniPath	No	No	Yes	No	No
secreted	secreted	Matrisome	No	No	Yes	No	No
secreted	secreted	OmniPath	No	No	Yes	No	No
ligand	ligand	Matrisome	Yes	No	Yes	No	No
ligand	ligand	OmniPath	Yes	No	Yes	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

2 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	ARG1 S100A14 S100A16	P05089 Q96FQ6 Q9HCY8	0:0:0	hu.MAP
	S100A14	Q9HCY8	2	PDB	PDB:2m0r

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential Ultracentrifugation	Mass spectrometryR Sequencing	1	35029059

Sequence, Structure & Domains

Sequences

Length

104

Mass

11,662

Sequence

MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERPVRGH

3D Structural Models

Turn

34..39; 55..57

Helix

19..32; 43..53; 60..62; 65..71; 81..94

Beta Strand

8..11; 98..100

3D Structure

NMR spectroscopy (1)

Domain & Motif Annotations

Domain (FT)

27..61; EF-hand

Protein Families

S-100 family

Sequence Similarities

Belongs to the S-100 family.

Clinical Relevance

Antibody

HPA027613