Protein detail
DCA16
DDB1- and CUL4-associated factor 16
Protein symbol DCA16 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
DDB1- and CUL4-associated factor 16
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C4orf30FLJ20280
Gene Description
DDB1 and CUL4 associated factor 16
Chromosome
4
Position
17800655-17810758
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue Specificblood vesselCell SpecificcDCSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell SpecificneutrophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Mediation Categories
Metabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 35399949 |
Sequence, Structure & Domains
Sequences
Length
216
Mass
24,193
Sequence
MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL
3D Structural Models
Turn
101..103; 190..192
Helix
48..60; 74..77; 88..94; 116..119; 131..138; 143..157; 179..186; 201..215
Beta Strand
64..67; 97..100
3D Structure
Electron microscopy (2)
Domain & Motif Annotations
Compositional Bias
29..41; Acidic residues
Region
1..42; Disordered
Clinical Relevance
Antibody
Interaction Protein
ENSG00000167986ENSG00000186767
Interaction Count
2
Interaction Dataset
biogrid_opencellbiogrid_bioplex