Protein detail
RHCG
Ammonium transporter Rh type C (Rh glycoprotein kidney) (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein) (Tumor-related protein DRC2)
Protein symbol RHCG | UniProt ID | EVMP score 0.38 |
Frequency | Transmembrane count 12 | Protein classification Metabolic proteinsPredicted membrane proteinsTransporters |
Basic Information
Protein Names
Ammonium transporter Rh type C (Rh glycoprotein kidney) (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein) (Tumor-related protein DRC2)
Protein Class
Metabolic proteinsPredicted membrane proteinsTransporters
Protein Function
Transporters:Transporter channels and pores
Transmembrane
10..30; Helical; 61..81; Helical; 86..106; Helical; 124..144; Helical; 149..169; Helical; 178..200; Helical; 219..239; Helical; 251..271; Helical; 282..302; Helical; 304..324; Helical; 346..366; Helical; 395..415; Helical
Transmembrane Count
12
Ensembl
Entrez Gene Symbol
Gene Synonym
C15orf6PDRC2RHGKSLC42A3
Gene Description
Rh family C glycoprotein
Chromosome
15
Position
89471398-89496589
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificcDCSingle-Nuclei Brain Specificendothelial cellSecretome LocationSecreted to bloodSecretome FunctionImmunity
Function & Pathway
Protein Function
Transporters:Transporter channels and pores
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
25 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | TopDB | No | No | No | No | No |
| transmembrane | transmembrane | LOCATE | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| apical_cell_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| apical_cell_membrane | plasma_membrane | Ramilowski_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | Ramilowski_location | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
479
Mass
53,179
Sequence
MAWNTNLRWRLPLTCLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLSDMENEFYYRYPSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQDRYIVVGVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGGSMTIHTFGAYFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAISYHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMMLMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAASASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPFWGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP
3D Structural Models
Turn
114..116; 181..184; 208..210; 236..239; 293..299; 440..442
Helix
10..29; 55..71; 73..77; 78..80; 85..109; 122..142; 148..170; 185..198; 204..207; 215..235; 243..270; 279..284; 285..287; 288..292; 303..332; 340..343; 345..360; 385..416; 432..434
Beta Strand
117..119
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Protein Families
- Ammonium transporter (TC 2.A.49) family
- Rh subfamily
Sequence Similarities
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.