Protein detail

NP1L2

Nucleosome assembly protein 1-like 2 (Brain-specific protein, X-linked) (Histone chaperone NAP1L2)

Entry name
NP1L2
UniProt ID
EVMP score
0.38
Frequency
2
Transmembrane count
Protein classification
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Nucleosome assembly protein 1-like 2 (Brain-specific protein, X-linked) (Histone chaperone NAP1L2)
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Tissue Specificblood vesselCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificvascular associated smooth muscle cellBlood Cell SpecificNK-cellBlood Lineage Specificdendritic cells
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

5 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularLOCATENoNoNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

12 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
FBLNAP1L2SRFBP1ZNF93P22087P35789Q8NEF9Q9ULW60:0:0:0hu.MAP
FBLNAP1L2TGS1ZNF93P22087P35789Q96RS0Q9ULW60:0:0:0hu.MAP
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Isolation & Detection Technology

0 records.

Sequence, Structure & Domains

Sequences

Length
460
Mass
52,542
Sequence
MAESENRKELSESSQEEAGNQIMVEGLGEHLERGEDAAAGLGDDGKCGEEAAAGLGEEGENGEDTAAGSGEDGKKGGDTDEDSEADRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQTRAANLESKFLREFHDIERKFAEMYQPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEMCHEEMYGNEEGMVHEYVDEDDGYEDYYYDYAVEEEEEEEEEDDIEATGEENKEEEDPKGIPDFWLTVLKNVDTLTPLIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLAYYDPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRTVTEDFPKDSFFNFFSPHGITSNGRDGNDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDNWMAAIEEVKACCKNLEALVEDIDR
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9ULW6-1; Sequence=Displayed; Name=2; IsoId=Q9ULW6-2; Sequence=VSP_057064
Alternative Sequence
1..142; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias
1..11; Basic and acidic residues; 27..36; Basic and acidic residues; 214..236; Acidic residues
Motif
346..352; Nuclear localization signal
Region
1..88; Disordered; 214..238; Disordered
Protein Families
Nucleosome assembly protein (NAP) family
Sequence Similarities
Belongs to the nucleosome assembly protein (NAP) family.
Clinical Relevance