Protein detail
NP1L2
Nucleosome assembly protein 1-like 2 (Brain-specific protein, X-linked) (Histone chaperone NAP1L2)
Entry name NP1L2 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 2 | Transmembrane count | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Nucleosome assembly protein 1-like 2 (Brain-specific protein, X-linked) (Histone chaperone NAP1L2)
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Supporting publications (n)
2
EVMP confidence score
0.40
Fluorescence & Localization
Tissue Specificblood vesselCell SpecificAlveolar cells type 1Single-Nuclei Brain Specificvascular associated smooth muscle cellBlood Cell SpecificNK-cellBlood Lineage Specificdendritic cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (2)
Molecular Function (4)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence17
Ligand-Receptor Signaling (5)
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | LOCATE | |||||
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Sequence, Structure & Domains
Sequences
Length
460
Mass
52,542
Sequence
MAESENRKELSESSQEEAGNQIMVEGLGEHLERGEDAAAGLGDDGKCGEEAAAGLGEEGENGEDTAAGSGEDGKKGGDTDEDSEADRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQTRAANLESKFLREFHDIERKFAEMYQPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEMCHEEMYGNEEGMVHEYVDEDDGYEDYYYDYAVEEEEEEEEEDDIEATGEENKEEEDPKGIPDFWLTVLKNVDTLTPLIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLAYYDPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRTVTEDFPKDSFFNFFSPHGITSNGRDGNDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDNWMAAIEEVKACCKNLEALVEDIDR
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9ULW6-1; Sequence=Displayed; Name=2; IsoId=Q9ULW6-2; Sequence=VSP_057064
Alternative Sequence
1..142; Missing (in isoform 2)
Domain & Motif Annotations
Compositional Bias
1..11; Basic and acidic residues; 27..36; Basic and acidic residues; 214..236; Acidic residues
Motif
346..352; Nuclear localization signal
Region
1..88; Disordered; 214..238; Disordered
Protein Families
Nucleosome assembly protein (NAP) family
Sequence Similarities
Belongs to the nucleosome assembly protein (NAP) family.
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 33304478 | The proteomic landscape of small urinary extracellular vesicles during kidney transplantation. | No related sentences available |
| 40189497 | Small extracellular vesicle-based one-step high-throughput microfluidic platform for epithelial ovarian cancer diagnosis. | No related sentences available |