Protein detail
PCDGJ
Protocadherin gamma-B7 (PCDH-gamma-B7)
Protein symbol PCDGJ | UniProt ID | EVMP score 0.50 |
Frequency 4 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
Basic Information
Protein Names
Protocadherin gamma-B7 (PCDH-gamma-B7)
Protein Class
Predicted membrane proteins
Transmembrane
692..712; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
ME6PCDH-GAMMA-B7
Gene Description
Protocadherin gamma subfamily B, 7
Chromosome
5
Position
141417645-141512975
Frequency
4
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificNeutrophilsBlood Cell SpecificneutrophilBlood Lineage Specificgranulocytes
Function & Pathway
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
- M13 Pid erbb4 pathway
- M236 Pid delta np63 pathway
- M256 Pid tap63 pathway
Mediation Categories
Adhesion and uptake mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
24 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| adhesion | adhesion | OmniPath | Yes | Yes | No | Yes | No |
| cell_adhesion | cell_adhesion | OmniPath | Yes | Yes | No | Yes | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | Yes | No |
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | No | No | No | Yes | No |
Regulatory Interaction Network
2 records.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| PCDA2 | Q9Y5H9 | PCDGJ | Q9Y5F8 | Yes | Yes | No | SIGNOR | SIGNOR:16697637 |
| PCDAA | Q9Y5I2 | PCDGJ | Q9Y5F8 | Yes | Yes | No | SIGNOR | SIGNOR:16697637 |
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | Mass spectrometry | 1 | 38343172 |
Sequence, Structure & Domains
Sequences
Length
929
Mass
100,974
Sequence
MGGSCAQRRRAGPRQVLFPLLLPLFYPTLCEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEAKDRGSLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESVLCSKSGPVGPPNYSEGTLPYAYNFCVPGDQMNPEFNFFTSVDHCPATQDNLNKDSMLLASILTPSVEADKKILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y5F8-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=Q9Y5F8-2; Sequence=VSP_008696, VSP_008697
Alternative Sequence
806..808; QAP -> VSI (in isoform 2); 809..929; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
807..838; Polar residues; 919..929; Basic residues
Domain (FT)
31..133; Cadherin 1; 134..242; Cadherin 2; 243..347; Cadherin 3; 348..452; Cadherin 4; 453..562; Cadherin 5; 570..675; Cadherin 6
Region
806..838; Disordered; 899..929; Disordered