Protein detail

CEAM7

Cell adhesion molecule CEACAM7 (Carcinoembryonic antigen CGM2) (Carcinoembryonic antigen-related cell adhesion molecule 7) (CEA cell adhesion molecule 7)

Protein symbol
CEAM7
UniProt ID
EVMP score
0.50
Frequency
1
Transmembrane count
Protein classification
Predicted membrane proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Cell adhesion molecule CEACAM7 (Carcinoembryonic antigen CGM2) (Carcinoembryonic antigen-related cell adhesion molecule 7) (CEA cell adhesion molecule 7)
Protein Class
Predicted membrane proteins
Entrez Gene Symbol
Gene Synonym
CEACGM2
Gene Description
CEA cell adhesion molecule 7
Chromosome
19
Position
41673303-41706976
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificbone marrowCell SpecificcDCSingle-Nuclei Brain Specificcentral nervous system macrophage
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembraneOmniPathNoNoNoNoNo
peripheralperipheralUniProt_locationNoNoNoNoNo
peripheralperipheralOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneCellinkerNoNoNoNoNo
apical_cell_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo
cell_surfacecell_surfaceSurfaceomeNoNoNoNoNo
cell_surfacecell_surfaceOmniPathNoNoNoNoNo
transmembranetransmembrane_predictedPhobiusNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
CEACAM7Q140024PDBPDB:4y89

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry136337342
Sequence, Structure & Domains

Sequences

Length
265
Mass
29,345
Sequence
MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGIYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMALI
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=2a; IsoId=Q14002-1; Sequence=Displayed; Name=2b; IsoId=Q14002-2; Sequence=VSP_002488
Alternative Sequence
143..235; Missing (in isoform 2b)

3D Structural Models

Turn
84..87
Helix
75..77; 115..117
Beta Strand
37..46; 51..56; 62..71; 78..83; 100..102; 108..110; 119..127; 133..142
3D Structure
X-ray crystallography (1)

Domain & Motif Annotations

Domain (FT)
36..142; Ig-like V-type; 146..233; Ig-like C2-type
Protein Families
  • Immunoglobulin superfamily
  • CEA family
Sequence Similarities
Belongs to the immunoglobulin superfamily. CEA family.
Clinical Relevance