Protein detail

S43A3

Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)

Entry name
S43A3
UniProt ID
Q8NBI5
EVMP confidence score
0.60
Supporting publications (n)
13
Transmembrane count
12
Protein classification
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Basic Information
Protein Names
Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)
Protein Class (3)
Predicted intracellular proteinsPredicted membrane proteinsTransporters
Protein Function (2)
  • Transporters:Electrochemical Potential-driven transporters
  • Predicted intracellular proteins
Transmembrane
17..37; Helical; 72..92; Helical; 102..122; Helical; 123..143; Helical; 156..176; Helical; 188..208; Helical; 279..299; Helical; 319..339; Helical; 356..376; Helical; 396..418; Helical; 427..447; Helical; 456..476; Helical
Transmembrane Count
12
Ensembl
ENSG00000134802
Entrez Gene Symbol
SLC43A3
Gene Synonym (5)
DKFZp762A227Eeg1FOAP-13PRO1659SEEEG-1
Gene Description
Solute carrier family 43 member 3
Chromosome
11
Position
57406954-57427580
Supporting publications (n)
13
EVMP confidence score
0.60
Function & Pathway
Protein Function (2)
  • Transporters:Electrochemical Potential-driven transporters
  • Predicted intracellular proteins
Cellular Component
GO:0016323 basolateral plasma membrane
Molecular Function (5)
Mediation Categories (2)
Clinical-translation mediationFusion and delivery mediation
Relations & Evidence22

Ligand-Receptor Signaling (21)

21 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembraneUniProt_keyword
transmembranetransmembraneTopDB
transmembranetransmembraneRamilowski_location
transmembranetransmembraneOmniPath
plasma_membraneplasma_membraneUniProt_location
basolateral_cell_membraneplasma_membraneUniProt_location
plasma_membraneplasma_membraneOmniPath
cell_surfacecell_surfaceSurfaceome
cell_surfacecell_surfaceOmniPath
receptorreceptorscConnectYes
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Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometryWestern blotting431508500337095103792230033709510
Sequence, Structure & Domains

Sequences

Length
491
Mass
54,529
Sequence
MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQADCKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFISVCSTWHVARTFLLMPRGHIPYPLPPNYSYGLCPGNGTTKEEKETAEHENRELQSKEFLSAKEETPGAGQKQELRSFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMARVSTYTNAFAFTQFGVLCAPWNGLLMDRLKQKYQKEARKTGSSTLAVALCSTVPSLALTSLLCLGFALCASVPILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLAILLTFFHPFLVYRECRTWKESPSAIA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NBI5-1; Sequence=Displayed; Name=2; IsoId=Q8NBI5-2; Sequence=VSP_055620
Alternative Sequence
61; A -> AGRLGCMGDLFSTP (in isoform 2)

Domain & Motif Annotations

Protein Families
SLC43A transporter (TC 2.A.1.44) family
Sequence Similarities
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
Clinical Relevance
Antibody (2)
HPA030551HPA077244
Interaction Protein
ENSG00000165280
Interaction Count
1
Interaction Dataset
intact_biogrid
Supporting Publications13
PMIDTitleRelated sentences
39558134Serum small extracellular vesicles-derived BST2 as a biomarker for papillary thyroid microcarcinoma promotes lymph node metastasis.No related sentences available
39766158A Proteomic Examination of Plasma Extracellular Vesicles Across Colorectal Cancer Stages Uncovers Biological Insights That Potentially Improve Prognosis.No related sentences available
39948040Quantitative proteomics identifies possible flow of metastatic cues between progressive stages of colorectal cancer via transfer of ceramide-dependent exosomal cargoes.No related sentences available
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