Protein detail
SYNCI
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Protein symbol SYNCI | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
SYNC1SYNCOILIN
Gene Description
Syncoilin, intermediate filament protein
Chromosome
1
Position
32679906-32703596
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificAstrocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
33 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometryWestern blotting | 0 |
Sequence, Structure & Domains
Sequences
Length
482
Mass
55,299
Sequence
MASPEPRRGGDGAAQAARKTRVEANSPLPKNSGSLNEAEALNPEVTLSSEGSLNLEDILYLEDTGDLDETLYVQETEKAEEALYIEEAMQPDEALHVEEPGNPEETVCVEETTEPDRIQFVEGPVEPGKPTSPEHVVYEGETVTRAEKSNPEESLRAEQSPSMEENLSIEDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAELERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKAMLLPKSLEQADAPTSQAGGMETQSQGAV
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H7C4-1; Sequence=Displayed; Name=2; IsoId=Q9H7C4-2; Sequence=VSP_039404
Alternative Sequence
454..482; AMLLPKSLEQADAPTSQAGGMETQSQGAV -> GCLEIYGQICNPETAKNFLAKDH (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
1..10; Basic and acidic residues; 144..156; Basic and acidic residues; 466..482; Polar residues
Domain (FT)
168..463; IF rod
Region
1..161; Head; 1..42; Disordered; 144..165; Disordered; 170..204; Coil 1A; 205..231; Linker 1; 232..309; Coil 1b; 310..349; Linker 2; 350..458; Coil 2; 459..482; Tail; 460..482; Disordered
Protein Families
Intermediate filament family
Sequence Similarities
Belongs to the intermediate filament family.