Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| ITA5 | P08648 | Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain] | Cancer-related genesCD markersPlasma proteins | 1 | Allergic/hypersensitivity disorderAsthmaMultiple sclerosis | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 5 | 0.25 | ||
| MRC1 | P22897 | Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) | CD markersFDA approved drug targetsPlasma proteins | 1 | COVID-19Type 2 diabetes mellitus | Adhesion and uptake mediationClinical-translation mediationImmune mediation | 5 | 0.25 | ||
| S26A2 | P50443 | Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2) | Disease related genesHuman disease related genesMetabolic proteins | 8 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 5 | 0.25 | |||
| MRP2 | Q92887 | ATP-binding cassette sub-family C member 2 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multidrug resistance protein) (Canalicular multispecific organic anion transporter 1) (Multidrug resistance-associated protein 2) | Cancer-related genesDisease related genesEnzymes | 17 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 4 | 0.25 | |||
| NRP1 | O14786 | Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304) | Cancer-related genesCD markersPlasma proteins | 1 | RetinopathySolid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 4 | 0.25 | ||
| P2RX4 | Q99571 | P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) | FDA approved drug targetsPredicted membrane proteinsTransporters | 2 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 4 | 0.25 | |||
| P2RY8 | Q86VZ1 | S-geranylgeranyl-glutathione receptor P2RY8 (P2Y purinoceptor 8) (P2Y8) | Cancer-related genesG-protein coupled receptorsPredicted intracellular proteins | 7 | Receptor-signaling mediation | 4 | 0.25 | |||
| SATT | P43007 | Neutral amino acid transporter A (Alanine/serine/cysteine/threonine transporter 1) (ASCT-1) (Solute carrier family 1 member 4) | Disease related genesHuman disease related genesMetabolic proteins | 8 | Fusion and delivery mediation | 4 | 0.25 | |||
| SCN4B | Q8IWT1 | Sodium channel regulatory subunit beta-4 | Disease related genesFDA approved drug targetsHuman disease related genes | 1 | Clinical-translation mediationFusion and delivery mediation | 4 | 0.25 | |||
| EPHA1 | P21709 | Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH) | Cancer-related genesEnzymesPlasma proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation | 3 | 0.25 | |||
| ESAM | Q96AP7 | Endothelial cell-selective adhesion molecule | Plasma proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 3 | 0.25 | |||
| HLAB | P01889 | HLA class I histocompatibility antigen, B alpha chain (Human leukocyte antigen B) (HLA-B) | Cancer-related genesDisease related genesHuman disease related genes | 1 | Melanoma | Clinical-translation mediationFusion and delivery mediationImmune mediation | 3 | 0.25 | ||
| HYAL2 | Q12891 | Hyaluronidase-2 (Hyal-2) (EC 3.2.1.35) (Hyaluronoglucosaminidase-2) (Lung carcinoma protein 2) (LuCa-2) | EnzymesMetabolic proteinsPredicted intracellular proteins | Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation | 3 | 0.25 | ||||
| ITAL | P20701 | Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD antigen CD11a) | CD markersFDA approved drug targetsPredicted intracellular proteins | 1 | Conjunctiva disorderDiabetes mellitusHuman immunodeficiency virus disease | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 3 | 0.25 | ||
| ITB6 | P18564 | Integrin beta-6 | Cancer-related genesDisease related genesHuman disease related genes | 1 | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 3 | 0.25 | ||
| LDLR | P01130 | Low-density lipoprotein receptor (LDL receptor) | Disease related genesHuman disease related genesMetabolic proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 3 | 0.25 | |||
| PD1L2 | Q9BQ51 | Programmed cell death 1 ligand 2 (PD-1 ligand 2) (PD-L2) (PDCD1 ligand 2) (Programmed death ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273) | Cancer-related genesCD markersPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 3 | 0.25 | |||
| SC6A2 | P23975 | Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) | Disease related genesFDA approved drug targetsHuman disease related genes | 12 | Clinical-translation mediationFusion and delivery mediation | 3 | 0.25 | |||
| TSHR | P16473 | Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R) | Cancer-related genesDisease related genesFDA approved drug targets | 7 | Hypo-thyroidismThyroid cancer | Clinical-translation mediationMetabolism mediationReceptor-signaling mediation | 3 | 0.25 | ||
| 5HT2B | P41595 | 5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Anxiety disorderAttention deficit hyperactivity disorderCoronary atherosclerosis | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.25 | ||
| ACE | P12821 | Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form] | Candidate cardiovascular disease genesCD markersDisease related genes | 1 | AsthmaCardiovascular diseaseChronic kidney disease | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.25 | ||
| ADA2C | P18825 | Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Acute diabete complicationAlzheimer diseaseAsthma | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.25 | ||
| AVR2A | P27037 | Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA) | Cancer-related genesEnzymesPredicted membrane proteins | 1 | Acute myeloid leukaemiaIdiopathic inflammatory myopathyMuscle disorder | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 2 | 0.25 | ||
| CD27 | P26842 | CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27) | Cancer-related genesCD markersDisease related genes | 1 | Brain cancerColorectal cancerHead and neck cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.25 | ||
| CD79A | P11912 | B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a) | Cancer-related genesCD markersDisease related genes | 1 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.25 |