Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| SMO | Q99835 | Protein smoothened (Protein Gx) | Cancer-related genesDisease related genesFDA approved drug targets | 7 | Basal cell carcinomaBrain cancerChronic myelomonocytic leukaemia | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | ||
| SO1A2 | P46721 | Solute carrier organic anion transporter family member 1A2 (OATP1A2) (OATP-A) (Organic anion-transporting polypeptide 1) (OATP-1) (Sodium-independent organic anion transporter) (Solute carrier family 21 member 3) | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | ||||
| SO1B1 | Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 (SLCO1B1) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C) (Organic anion transporter SLC21A6) (Sodium-independent organic anion-transporting polypeptide 2) (OATP-2) (Solute carrier family 21 member 6) | Disease related genesHuman disease related genesMetabolic proteins | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | |||
| SO1B3 | Q9NPD5 | Solute carrier organic anion transporter family member 1B3 (Liver-specific organic anion transporter 2) (LST-2) (OATP1B3) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP-8) (Solute carrier family 21 member 8) | Disease related genesHuman disease related genesMetabolic proteins | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | |||
| SO5A1 | Q9H2Y9 | Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15) | Predicted membrane proteinsTransporters | 12 | Fusion and delivery mediation | 1 | 0.50 | |||
| SORC3 | Q9UPU3 | VPS10 domain-containing receptor SorCS3 | 1 | Receptor-signaling mediation | 1 | 0.50 | ||||
| SPPL3 | Q8TCT6 | Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin homologous protein 1) (PSH1) (Presenilin-like protein 4) | EnzymesPredicted membrane proteins | 9 | Fusion and delivery mediationImmune mediationMetabolism mediation | 1 | 0.50 | |||
| SR5A3 | Q9H8P0 | Polyprenal reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3) | Disease related genesEnzymesHuman disease related genes | 6 | Clinical-translation mediationMetabolism mediation | 1 | 0.50 | |||
| SSR5 | P35346 | Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R) (SST5) | 7 | Alzheimer diseaseCushing syndromeStomach cancer | Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation | 1 | 0.50 | |||
| STEA4 | Q687X5 | Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9) | 6 | Fusion and delivery mediation | 1 | 0.50 | ||||
| STX4 | Q12846 | Syntaxin-4 (Renal carcinoma antigen NY-REN-31) | Predicted intracellular proteinsPredicted membrane proteinsTransporters | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| SUN3 | Q8TAQ9 | SUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1) | Predicted intracellular proteinsPredicted membrane proteins | 1 | Other mediation | 1 | 0.50 | |||
| SYCY2 | P60508 | Syncytin-2 (Endogenous retrovirus group FRD member 1) (Envelope polyprotein) (HERV-FRD) (HERV-FRD_6p24.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)] | 1 | Other mediation | 1 | 0.50 | ||||
| T183A | Q8IXX5 | Transmembrane protein 183A | 1 | Other mediation | 1 | 0.50 | ||||
| T229A | B2RXF0 | Transmembrane protein 229A | Predicted membrane proteins | 6 | Other mediation | 1 | 0.50 | |||
| T2R10 | Q9NYW0 | Taste receptor type 2 member 10 (T2R10) (Taste receptor family B member 2) (TRB2) | 7 | Receptor-signaling mediation | 1 | 0.50 | ||||
| T4S18 | Q96CE8 | Transmembrane 4 L6 family member 18 | Predicted membrane proteinsTransporters | 4 | Other mediation | 1 | 0.50 | |||
| T4S20 | Q53R12 | Transmembrane 4 L6 family member 20 | Disease related genesPotential drug targetsPredicted intracellular proteins | 4 | Adhesion and uptake mediation | 1 | 0.50 | |||
| T4S4 | P48230 | Transmembrane 4 L6 family member 4 (Intestine and liver tetraspan membrane protein) (IL-TMP) | Predicted membrane proteinsTransporters | 4 | Other mediation | 1 | 0.50 | |||
| T4S5 | O14894 | Transmembrane 4 L6 family member 5 (Tetraspan transmembrane protein L6H) | 4 | Fusion and delivery mediation | 1 | 0.50 | ||||
| TA2R | P21731 | Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor) | 7 | Angina pectorisArterial occlusive diseaseAsthma | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 1 | 0.50 | |||
| TEN1 | Q9UKZ4 | Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)] | Predicted membrane proteinsTransporters | 1 | Fusion and delivery mediationReceptor-signaling mediation | 1 | 0.50 | |||
| TGFR1 | P36897 | TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) | Disease related genesEnzymesHuman disease related genes | 1 | Arterial occlusive diseaseBrain cancerCachexia | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | ||
| TGFR2 | P37173 | TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) | 1 | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | |||
| TIE2 | Q02763 | Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b) | Cancer-related genesCD markersDisease related genes | 1 | Breast cancerChronic arterial occlusive diseaseIschemia | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 |