Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| ATP4A | P20648 | Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump) | EnzymesFDA approved drug targetsMetabolic proteins | 10 | Bacterial infectionCardiovascular diseaseColorectal cancer | Clinical-translation mediationFusion and delivery mediation | 0.38 | |||
| B3AT | P02730 | Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233) | Blood group antigen proteinsCD markersDisease related genes | 12 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 0.38 | ||||
| BT3A2 | P78410 | Butyrophilin subfamily 3 member A2 | Predicted intracellular proteinsPredicted membrane proteins | 1 | Fusion and delivery mediationImmune mediation | 0.38 | ||||
| CAD23 | Q9H251 | Cadherin-23 (Otocadherin) | Disease related genesHuman disease related genesPredicted intracellular proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation | 0.38 | ||||
| CCR5 | P51681 | C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195) | 7 | Chronic kidney diseaseChronic obstructive pulmonary diseaseDiabetes mellitus | Clinical-translation mediationFusion and delivery mediationImmune mediation | 0.38 | ||||
| CD1A | P06126 | T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a) | CD markersPredicted membrane proteins | 1 | Aplastic anaemiaAtopic eczema | Clinical-translation mediationFusion and delivery mediationImmune mediation | 0.38 | |||
| CDHR2 | Q9BYE9 | Cadherin-related family member 2 (Protocadherin LKC) (PC-LKC) (Protocadherin-24) | Plasma proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediation | 0.38 | ||||
| CDHR5 | Q9HBB8 | Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein) (Mucin-like protocadherin) (MLPCDH) | Plasma proteinsPredicted intracellular proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediation | 0.38 | ||||
| CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel) | Cancer-related genesDisease related genesEnzymes | 12 | Bowel habit changeChronic obstructive pulmonary diseaseCystic fibrosis | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 0.38 | |||
| CLD1 | O95832 | Claudin-1 (Senescence-associated epithelial membrane protein) | Disease related genesHuman disease related genesPotential drug targets | 4 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| CLD5 | O00501 | Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF) | Predicted membrane proteinsTransporters | 4 | Adhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation | 0.38 | ||||
| CLD6 | P56747 | Claudin-6 (Skullin) | 4 | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| CNGA1 | P29973 | Cyclic nucleotide-gated channel alpha-1 (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated cation channel subunit alpha) (cGMP-gated cation channel alpha-1) | 7 | Myelopathy | Clinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| COPT1 | O15431 | High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form] | Metabolic proteinsPredicted membrane proteinsTransporters | 3 | Clinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| CTL4 | Q53GD3 | Choline transporter-like protein 4 (Solute carrier family 44 member 4) (Thiamine pyrophosphate transporter 1) (hTPPT1) | Disease related genesHuman disease related genesMetabolic proteins | 10 | Pancreatic cancerProstate cancer | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 0.38 | |||
| CXB1 | P08034 | Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein) | Disease related genesHuman disease related genesPotential drug targets | 4 | Fusion and delivery mediation | 0.38 | ||||
| CXCR4 | P61073 | C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184) | 7 | Acute myeloid leukaemiaBreast cancerChronic arterial occlusive disease | Clinical-translation mediationFusion and delivery mediationImmune mediation | 0.38 | ||||
| DPP4 | P27487 | Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] | CD markersEnzymesFDA approved drug targets | 1 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| DSG1 | Q02413 | Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen) | Disease related genesHuman disease related genesPlasma proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 0.38 | ||||
| DUOX2 | Q9NRD8 | Dual oxidase 2 (EC 1.-.-.-) (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 2) (Long NOX 2) (NADH/NADPH thyroid oxidase p138-tox) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (p138 thyroid oxidase) | 7 | Fusion and delivery mediationImmune mediationMetabolism mediation | 0.38 | |||||
| EAA3 | P43005 | Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1) | Disease related genesHuman disease related genesMetabolic proteins | 8 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 0.38 | ||||
| FCERG | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma (Fc receptor gamma-chain) (FcRgamma) (Fc-epsilon RI-gamma) (IgE Fc receptor subunit gamma) (FceRI gamma) | FDA approved drug targetsPredicted membrane proteins | 1 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 0.38 | ||||
| FXYD3 | Q14802 | FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) | Predicted intracellular proteinsPredicted membrane proteinsTransporters | 1 | Fusion and delivery mediation | 0.38 | ||||
| GPNMB | Q14956 | Transmembrane glycoprotein NMB (Hematopoietic growth factor inducible neurokinin-1 type) | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 0.38 | |||||
| HEPH | Q9BQS7 | Hephaestin (Hp) (EC 1.16.3.1) | Metabolic proteinsPredicted membrane proteinsTransporters | 1 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 0.38 |