Browse EV MemProt Atlas
- Frequency:
- literature support frequency.
- EVMP score:
annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| VGFR1 | P17948 | Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor) | Cancer-related genesDisease related genesEnzymesFDA approved drug targetsPlasma proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteins | 1 | Adhesion and uptake mediationClinical-translation mediationImmune mediationReceptor-signaling mediation | 1 | 0.50 | |||
| VIP1 | Q6PFW1 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 1) (Histidine acid phosphatase domain-containing protein 2A) (IP6 kinase) (Inositol pyrophosphate synthase 1) (InsP6 and PP-IP5 kinase 1) (VIP1 homolog) (hsVIP1) | EnzymesMetabolic proteinsPredicted intracellular proteins | Metabolism mediation | 1 | 0.50 | ||||
| VTCN1 | Q7Z7D3 | V-set domain-containing T-cell activation inhibitor 1 (B7 homolog 4) (B7-H4) (B7h.5) (Immune costimulatory protein B7-H4) (Protein B7S1) (T-cell costimulatory molecule B7x) | Predicted intracellular proteinsPredicted membrane proteins | 1 | Breast cancerSolid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | ||
| XPP2 | O43895 | Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2) | Disease related genesEnzymesPotential drug targetsPredicted intracellular proteins | Metabolism mediation | 1 | 0.50 | ||||
| XRP2 | O75695 | Protein XRP2 | Disease related genesHuman disease related genesPredicted intracellular proteins | Other mediation | 1 | 0.50 | ||||
| YES | P07947 | Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes) | EnzymesFDA approved drug targetsPlasma proteinsPredicted intracellular proteins | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation | 1 | 0.50 | ||||
| ZBED3 | Q96IU2 | Zinc finger BED domain-containing protein 3 (Axin-interacting protein) | Predicted intracellular proteinsPredicted secreted proteinsTranscription factors | Fusion and delivery mediationReceptor-signaling mediation | 1 | 0.50 | ||||
| ZDH20 | Q5W0Z9 | Palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Acyltransferase ZDHHC20) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 20) (DHHC20) (Zinc finger DHHC domain-containing protein 20) | EnzymesMetabolic proteinsPredicted membrane proteinsTransporters | 4 | Clinical-translation mediation | 1 | 0.50 | |||
| ZDHC2 | Q9UIJ5 | Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Acyltransferase ZDHHC2) (EC 2.3.1.-) (Reduced expression associated with metastasis protein) (Ream) (Reduced expression in cancer protein) (Rec) (Zinc finger DHHC domain-containing protein 2) (DHHC-2) (Zinc finger protein 372) | EnzymesMetabolic proteinsPredicted intracellular proteinsPredicted membrane proteins | 4 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediationMetabolism mediationReceptor-signaling mediation | 1 | 0.50 | |||
| ZO2 | Q9UDY2 | Tight junction protein 2 (Tight junction protein ZO-2) (Zona occludens protein 2) (Zonula occludens protein 2) | Cancer-related genesDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteins | Adhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation | 1 | 0.50 | ||||
| RAB35 | Q15286 | Ras-related protein Rab-35 (EC 3.6.5.2) (GTP-binding protein RAY) (Ras-related protein Rab-1C) | Predicted intracellular proteins | Fusion and delivery mediationImmune mediationMetabolism mediationReceptor-signaling mediation | 0.50 | |||||
| CC50B | Q3MIR4 | Cell cycle control protein 50B (P4-ATPase flippase complex beta subunit TMEM30B) (Transmembrane protein 30B) | Predicted membrane proteinsTransporters | 2 | Fusion and delivery mediation | 20 | 0.47 | |||
| CBPD | O75976 | Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) | EnzymesPredicted intracellular proteinsPredicted membrane proteins | 1 | Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation | 16 | 0.47 | |||
| ITM2B | Q9Y287 | Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)] | Disease related genesHuman disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsTransporters | 1 | Fusion and delivery mediationMetabolism mediation | 16 | 0.47 | |||
| STIM1 | Q13586 | Stromal interaction molecule 1 | Disease related genesHuman disease related genesPlasma proteinsPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransporters | 1 | Fusion and delivery mediationImmune mediationMetabolism mediationReceptor-signaling mediation | 15 | 0.47 | |||
| CD82 | P27701 | CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82) | Cancer-related genesCD markersPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | 4 | Clinical-translation mediationFusion and delivery mediation | 14 | 0.47 | |||
| DRB4 | P13762 | HLA class II histocompatibility antigen, DR beta 4 chain (MHC class II antigen DRB4) | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 14 | 0.47 | ||||
| PPBT | P05186 | Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNS-ALP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) | Cancer-related genesDisease related genesEnzymesHuman disease related genesMetabolic proteinsPlasma proteinsPotential drug targetsPredicted intracellular proteinsPredicted membrane proteins | Colon cancerGenetic prion diseaseMineral absorption/transport disorderParasitic infectionPseudoxanthoma elasticum | Clinical-translation mediationImmune mediationMetabolism mediation | 14 | 0.47 | |||
| TSN8 | P19075 | Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor-associated antigen CO-029) | Cancer-related genesPredicted membrane proteins | 4 | Immune mediation | 14 | 0.47 | |||
| ADCY6 | O43306 | Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase) | Disease related genesEnzymesHuman disease related genesMetabolic proteinsPredicted intracellular proteinsPredicted membrane proteins | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediationReceptor-signaling mediation | 12 | 0.47 | |||
| CAD11 | P55287 | Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin) | Cancer-related genesDisease related genesHuman disease related genesPredicted intracellular proteinsPredicted membrane proteins | 1 | Rheumatoid arthritis | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediationReceptor-signaling mediation | 12 | 0.47 | ||
| CBPM | P14384 | Carboxypeptidase M (CPM) (EC 3.4.17.12) | EnzymesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Metabolism mediation | 12 | 0.47 | ||||
| CD22 | P20273 | B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22) | CD markersFDA approved drug targetsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | 1 | Acute myeloid leukaemiaB-cell lymphomaDiabetes mellitusDiffuse large B-cell lymphomaFollicular lymphomaLeukaemiaLupus erythematosusLyme borreliosisLymphomaMalignant haematopoietic neoplasmMature B-cell leukaemiaMature B-cell lymphomaMultiple myelomaTransplant rejection | Clinical-translation mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation | 12 | 0.47 | ||
| NLGN2 | Q8NFZ4 | Neuroligin-2 | Predicted intracellular proteinsPredicted membrane proteinsTransporters | 1 | Adhesion and uptake mediationFusion and delivery mediation | 12 | 0.47 | |||
| CAD17 | Q12864 | Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin) | Cancer-related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation | 11 | 0.47 |