Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| PSCA | O43653 | Prostate stem cell antigen | Cancer-related genesPredicted intracellular proteinsPredicted membrane proteins | Non-small-cell lung cancerPancreatic cancerProstate cancer | Clinical-translation mediationMetabolism mediationReceptor-signaling mediation | 2 | 0.50 | |||
| PTAFR | P25105 | Platelet-activating factor receptor (PAF-R) (PAFr) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Allergic/hypersensitivity disorderAsthmaCardiac arrhythmia | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | ||
| RAPSN | Q13702 | 43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205) | Disease related genesHuman disease related genesPredicted intracellular proteins | Adhesion and uptake mediation | 2 | 0.50 | ||||
| RHOA | P61586 | Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12) | Cancer-related genesDisease related genesEnzymes | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | |||
| S13A5 | Q86YT5 | Na(+)/citrate cotransporter (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter) (Solute carrier family 13 member 5) | Disease related genesHuman disease related genesMetabolic proteins | 11 | Fusion and delivery mediation | 2 | 0.50 | |||
| S19A3 | Q9BZV2 | Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) | Disease related genesHuman disease related genesMetabolic proteins | 12 | Fusion and delivery mediationMetabolism mediation | 2 | 0.50 | |||
| S67A1 | Q96BI1 | Solute carrier family 67 member A1 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein) (Efflux transporter-like protein) (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Organic cation transporter-like protein 2) (ORCTL-2) (Solute carrier family 22 member 1-like) (Solute carrier family 22 member 18) (Tumor-suppressing STF cDNA 5 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (p45-Beckwith-Wiedemann region 1 A) (p45-BWR1A) | Disease related genesHuman disease related genesMetabolic proteins | 10 | Clinical-translation mediationFusion and delivery mediation | 2 | 0.50 | |||
| SI1L3 | O60292 | Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) | Disease related genesHuman disease related genesPredicted intracellular proteins | Fusion and delivery mediationReceptor-signaling mediation | 2 | 0.50 | ||||
| SLIK6 | Q9H5Y7 | SLIT and NTRK-like protein 6 | Disease related genesHuman disease related genesPredicted membrane proteins | 1 | Bladder cancerUreteral cancer | Clinical-translation mediation | 2 | 0.50 | ||
| SMOC1 | Q9H4F8 | SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1) | Disease related genesHuman disease related genesPredicted secreted proteins | Other mediation | 2 | 0.50 | ||||
| SSR3 | P32745 | Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SST3) (SSR-28) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Alzheimer diseaseCushing syndromeStomach cancer | Clinical-translation mediationReceptor-signaling mediation | 2 | 0.50 | ||
| STYK1 | Q6J9G0 | Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1) | EnzymesPredicted intracellular proteinsPredicted membrane proteins | 1 | Other mediation | 2 | 0.50 | |||
| TLR4 | O00206 | Toll-like receptor 4 (hToll) (CD antigen CD284) | CD markersFDA approved drug targetsHuman disease related genes | 1 | Allergic/hypersensitivity disorderDiabetes mellitusHepatitis virus infection | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | ||
| TMPS2 | O15393 | Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain] | Cancer-related genesEnzymesPredicted intracellular proteins | 1 | COVID-19Middle East Respiratory SyndromeSevere acute respiratory syndrome | Clinical-translation mediationMetabolism mediation | 2 | 0.50 | ||
| UPAR | Q03405 | Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) | Cancer-related genesCD markersFDA approved drug targets | Acquired hypomelanotic disorderAtopic eczemaMyeloproliferative neoplasm | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | |||
| ABCC9 | O60706 | ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2) | Disease related genesFDA approved drug targetsHuman disease related genes | 15 | Acute diabete complicationAngina pectorisMultiple sclerosis | Clinical-translation mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | ||
| ABCG2 | Q9UNQ0 | Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338) | Cancer-related genesCD markersEnzymes | 6 | Irritable bowel syndromeRheumatoid arthritis | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | ||
| ACKR3 | P25106 | Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1) | Cancer-related genesDisease related genesG-protein coupled receptors | 7 | AsthmaSolid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | ||
| ACTN1 | P12814 | Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1) | Disease related genesFDA approved drug targetsHuman disease related genes | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | ||||
| ADA | P00813 | Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) | Disease related genesEnzymesFDA approved drug targets | Adaptive immunity immunodeficiencyChronic painImmunodeficiency | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | |||
| ADA33 | Q9BZ11 | Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-) | Disease related genesHuman disease related genesPredicted membrane proteins | 1 | Receptor-signaling mediation | 1 | 0.50 | |||
| ADCY5 | O95622 | Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (AC5) | Disease related genesEnzymesHuman disease related genes | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | |||
| AGRG2 | Q8IZP9 | Adhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Human epididymis-specific protein 6) (He6) [Cleaved into: Adhesion G-protein coupled receptor G2, N-terminal fragment (ADGRG2 N-terminal fragment); Adhesion G-protein coupled receptor G2, C-terminal fragment (ADGRG2 C-terminal fragment)] | Disease related genesG-protein coupled receptorsHuman disease related genes | 7 | Fusion and delivery mediationReceptor-signaling mediation | 1 | 0.50 | |||
| AKA12 | Q02952 | A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) | Cancer-related genesPlasma proteinsPredicted intracellular proteins | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | ||||
| ALK | Q9UM73 | ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246) | Cancer-related genesCD markersDisease related genes | 1 | Adrenal cancerBreast cancerColorectal cancer | Clinical-translation mediationReceptor-signaling mediation | 1 | 0.50 |