Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
SMOQ99835Protein smoothened (Protein Gx)Cancer-related genesDisease related genesFDA approved drug targets7Basal cell carcinomaBrain cancerChronic myelomonocytic leukaemiaClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
SNP25P60880Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)Disease related genesFDA approved drug targetsHuman disease related genesEyelid inflammatory/movement disorderClinical-translation mediationFusion and delivery mediationImmune mediation10.50
SR5A3Q9H8P0Polyprenal reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)Disease related genesEnzymesHuman disease related genes6Clinical-translation mediationMetabolism mediation10.50
SRCP12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Cancer-related genesDisease related genesEnzymesAcute myeloid leukaemiaBCR-ABL1-negative chronic myeloid leukaemiaBrain cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
STX4Q12846Syntaxin-4 (Renal carcinoma antigen NY-REN-31)Predicted intracellular proteinsPredicted membrane proteinsTransporters1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
SVILO95425Supervillin (Archvillin) (p205/p250)Disease related genesHuman disease related genesPlasma proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
T4S20Q53R12Transmembrane 4 L6 family member 20Disease related genesPotential drug targetsPredicted intracellular proteins4Adhesion and uptake mediation10.50
TBC24Q9ULP9TBC1 domain family member 24Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation10.50
TGFR1P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)Disease related genesEnzymesHuman disease related genes1Arterial occlusive diseaseBrain cancerCachexiaClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
TIE2Q02763Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)Cancer-related genesCD markersDisease related genes1Breast cancerChronic arterial occlusive diseaseIschemiaAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
TM222Q9H0R3Transmembrane protein 222Disease related genesHuman disease related genesPredicted membrane proteins3Other mediation10.50
TM237Q96Q45Transmembrane protein 237 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein)Disease related genesHuman disease related genesPotential drug targets4Receptor-signaling mediation10.50
TNR11Q9Y6Q6Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)CD markersDisease related genesHuman disease related genes1Fusion and delivery mediationImmune mediationMetabolism mediation10.50
TNR12Q9NP84Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)Cancer-related genesCD markersPredicted intracellular proteins1Solid tumour/cancerClinical-translation mediationImmune mediationReceptor-signaling mediation10.50
TNR6P25445Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)Cancer-related genesCandidate cardiovascular disease genesCD markers1Brain cancerCerebral ischaemiaMature T-cell lymphomaClinical-translation mediationFusion and delivery mediationImmune mediation10.50
TRDNQ13061TriadinDisease related genesHuman disease related genesPlasma proteins1Fusion and delivery mediationMetabolism mediation10.50
TRPM7Q96QT4Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7) [Cleaved into: TRPM7 kinase, cleaved form (M7CK); TRPM7 channel, cleaved form]Disease related genesEnzymesEssential proteins6Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
TYRP2P40126L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2)Disease related genesEnzymesHuman disease related genes1Metabolism mediation10.50
VGFR1P17948Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)Cancer-related genesDisease related genesEnzymes1Adhesion and uptake mediationClinical-translation mediationImmune mediation10.50
XRP2O75695Protein XRP2Disease related genesHuman disease related genesPredicted intracellular proteinsOther mediation10.50
YESP07947Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)EnzymesFDA approved drug targetsPlasma proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
ZO2Q9UDY2Tight junction protein 2 (Tight junction protein ZO-2) (Zona occludens protein 2) (Zonula occludens protein 2)Cancer-related genesDisease related genesHuman disease related genesAdhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation10.50
ITM2BQ9Y287Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]Disease related genesHuman disease related genesPotential drug targets1Fusion and delivery mediationMetabolism mediation160.47
STIM1Q13586Stromal interaction molecule 1Disease related genesHuman disease related genesPlasma proteins1Fusion and delivery mediationImmune mediationMetabolism mediation150.47
CD82P27701CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)Cancer-related genesCD markersPlasma proteins4Clinical-translation mediationFusion and delivery mediation140.47

401-425 of 792 proteins

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