Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
MGAO43451Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20)EnzymesFDA approved drug targetsMetabolic proteins1Acute diabete complicationBlood chemistry clinical symptonCardiovascular diseaseClinical-translation mediationFusion and delivery mediationImmune mediation0.38
MUC17Q685J3Mucin-17 (MUC-17) (Small intestinal mucin-3) (MUC-3)Cancer-related genesPredicted membrane proteins1Oesophagogastric junction cancerStomach cancerClinical-translation mediationFusion and delivery mediationImmune mediation0.38
NPCL1Q9UHC9NPC1-like intracellular cholesterol transporter 1 (NPC1L1) (Niemann-Pick C1-like protein 1)FDA approved drug targetsMetabolic proteinsPredicted membrane proteins13Hyper-lipoproteinaemiaClinical-translation mediationFusion and delivery mediation0.38
ORAI1Q96D31Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)Disease related genesHuman disease related genesPotential drug targets4Fusion and delivery mediationImmune mediationReceptor-signaling mediation0.38
PKD1P98161Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein)Disease related genesHuman disease related genesPlasma proteins11Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation0.38
RAB18Q9NP72Ras-related protein Rab-18 (EC 3.6.5.2)Cancer-related genesDisease related genesHuman disease related genesFusion and delivery mediationImmune mediationMetabolism mediation0.38
S12A3P55017Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter)Disease related genesFDA approved drug targetsHuman disease related genes12Essential hypertensionHypertensionOedemaClinical-translation mediationFusion and delivery mediation0.38
S20A2Q08357Sodium-dependent phosphate transporter 2 (Gibbon ape leukemia virus receptor 2) (GLVR-2) (Phosphate transporter 2) (PiT-2) (Pit2) (hPit2) (Solute carrier family 20 member 2)Disease related genesHuman disease related genesMetabolic proteins12Clinical-translation mediationFusion and delivery mediation0.38
S22A6Q4U2R8Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1)FDA approved drug targetsMetabolic proteinsPredicted membrane proteins12Clinical-translation mediationFusion and delivery mediation0.38
S22A8Q8TCC7Organic anion transporter 3 (hOAT3) (Organic anion/dicarboxylate exchanger) (Solute carrier family 22 member 8)FDA approved drug targetsMetabolic proteinsPredicted membrane proteins11GoutHerpes simplex infectionInborn purine/pyrimidine/nucleotide metabolism errorClinical-translation mediationFusion and delivery mediation0.38
S22ABQ9NSA0Solute carrier family 22 member 11 (Organic anion transporter 4) (OAT4) (Organic anion:dicarboxylate exchanger OAT4)FDA approved drug targetsMetabolic proteinsPlasma proteins12Clinical-translation mediationFusion and delivery mediation0.38
S22ACQ96S37Solute carrier family 22 member 12 (Organic anion transporter 4-like protein) (Renal-specific transporter) (RST) (Urate anion exchanger 1) (URAT1) (Urate:anion antiporter SLC22A12)Disease related genesFDA approved drug targetsHuman disease related genes12Clinical-translation mediationFusion and delivery mediation0.38
S26A4O43511Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4)Disease related genesHuman disease related genesMetabolic proteins12Clinical-translation mediationFusion and delivery mediation0.38
S6A19Q695T7Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1)Disease related genesHuman disease related genesMetabolic proteins12Clinical-translation mediationFusion and delivery mediation0.38
SC5A2P31639Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2)Disease related genesFDA approved drug targetsHuman disease related genes14Clinical-translation mediationFusion and delivery mediation0.38
SNTA1Q13424Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation0.38
SUISP14410Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]Disease related genesEnzymesFDA approved drug targets1Clinical-translation mediationFusion and delivery mediation0.38
TBCDQ9BTW9Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)Disease related genesEssential proteinsHuman disease related genesAdhesion and uptake mediationFusion and delivery mediationMetabolism mediation0.38
TR10AO00220Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)Cancer-related genesCD markersPredicted membrane proteins1Fusion and delivery mediationImmune mediationReceptor-signaling mediation0.38
VATE1P36543V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)Disease related genesEssential proteinsHuman disease related genesFusion and delivery mediationImmune mediationReceptor-signaling mediation0.38
CD1DP15813Antigen-presenting glycoprotein CD1d (R3G1) (CD antigen CD1d)Cancer-related genesCD markersPredicted membrane proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation50.25
CD36P16671Platelet glycoprotein 4 (Fatty acid translocase) (FAT) (Glycoprotein IIIb) (GPIIIB) (Leukocyte differentiation antigen CD36) (PAS IV) (PAS-4) (Platelet collagen receptor) (Platelet glycoprotein IV) (GPIV) (Thrombospondin receptor) (CD antigen CD36)Cancer-related genesCD markersDisease related genes2Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.25
CD59P13987CD59 glycoprotein (1F5 antigen) (20 kDa homologous restriction factor) (HRF-20) (HRF20) (MAC-inhibitory protein) (MAC-IP) (MEM43 antigen) (Membrane attack complex inhibition factor) (MACIF) (Membrane inhibitor of reactive lysis) (MIRL) (Protectin) (CD antigen CD59)Cancer-related genesCD markersDisease related genesMacular degenerationRetinopathyAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.25
EXTL3O43909Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3)Disease related genesEnzymesHuman disease related genes1Immune mediationMetabolism mediationReceptor-signaling mediation50.25
GLUT4P14672Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4)Disease related genesMetabolic proteinsPotential drug targets12Type 2 diabetes mellitusClinical-translation mediationFusion and delivery mediationMetabolism mediation50.25

651-675 of 792 proteins

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