Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| 5HT1B | P28222 | 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Alzheimer diseaseAnxiety disorderAttention deficit hyperactivity disorder | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 2 | 0.50 | ||
| 5HT7R | P34969 | 5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7) | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | Alzheimer diseaseAttention deficit hyperactivity disorderBipolar disorder | Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation | 2 | 0.50 | ||
| ACHA3 | P32297 | Neuronal acetylcholine receptor subunit alpha-3 | Disease related genesFDA approved drug targetsPredicted intracellular proteins | 4 | Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation | 2 | 0.50 | |||
| ACK1 | Q07912 | Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2) | Cancer-related genesEnzymesPlasma proteins | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | ||||
| ACM3 | P20309 | Muscarinic acetylcholine receptor M3 | Disease related genesFDA approved drug targetsG-protein coupled receptors | 7 | Abnormal micturitionAlzheimer diseaseAsthma | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 2 | 0.50 | ||
| AP2M1 | Q96CW1 | AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | Disease related genesEssential proteinsHuman disease related genes | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | ||||
| APLD1 | Q96LR9 | Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein) | Predicted membrane proteins | 3 | Fusion and delivery mediation | 2 | 0.50 | |||
| AQP5 | P55064 | Aquaporin-5 (AQP-5) | Disease related genesHuman disease related genesMetabolic proteins | 6 | Fusion and delivery mediation | 2 | 0.50 | |||
| AT2B4 | P23634 | Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4) | EnzymesFDA approved drug targetsMetabolic proteins | 10 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | |||
| ATP4B | P51164 | Potassium-transporting ATPase subunit beta (Gastric H(+)/K(+) ATPase subunit beta) (Proton pump beta chain) | FDA approved drug targetsMetabolic proteinsPredicted membrane proteins | 1 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | |||
| CAD15 | P55291 | Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin) | Disease related genesHuman disease related genesPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation | 2 | 0.50 | |||
| CADH5 | P33151 | Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144) | Cancer-related genesCD markersPlasma proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation | 2 | 0.50 | |||
| CALRL | Q16602 | Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor) (CRLR) | Disease related genesFDA approved drug targetsG-protein coupled receptors | 7 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | |||
| CCD32 | Q9BV29 | Coiled-coil domain-containing protein 32 | Disease related genesHuman disease related genesPredicted intracellular proteins | Adhesion and uptake mediation | 2 | 0.50 | ||||
| CCR4 | P51679 | C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194) | CD markersFDA approved drug targetsG-protein coupled receptors | 7 | AsthmaDiabetes mellitusImmune system disease | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | ||
| CD28 | P10747 | T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28) | CD markersPredicted membrane proteins | 1 | Brain cancerDiabetes mellitusImmune system disease | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 | ||
| CD38 | P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (EC 3.2.2.-) (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase 1) (ADPRC 1) (Cyclic ADP-ribose hydrolase 1) (cADPR hydrolase 1) (T10) (CD antigen CD38) | Cancer-related genesCD markersEnzymes | 1 | Acute myeloid leukaemiaB-cell lymphomaMalignant haematopoietic neoplasm | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | ||
| CD3G | P09693 | T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g) | CD markersDisease related genesFDA approved drug targets | 1 | Breast cancerColorectal cancerMalignant digestive organ neoplasm | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | ||
| CLCN6 | P51797 | H(+)/Cl(-) exchange transporter 6 (Chloride channel protein 6) (ClC-6) (Chloride transport protein 6) | Disease related genesPlasma proteinsPredicted membrane proteins | 10 | Clinical-translation mediationFusion and delivery mediation | 2 | 0.50 | |||
| CNR1 | P21554 | Cannabinoid receptor 1 (CB-R) (CB1) (CANN6) | Disease related genesFDA approved drug targetsG-protein coupled receptors | 7 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | |||
| CYBC1 | Q9BQA9 | Cytochrome b-245 chaperone 1 (Essential for reactive oxygen species protein) (Eros) | Disease related genesHuman disease related genesPredicted intracellular proteins | 1 | Other mediation | 2 | 0.50 | |||
| DIAP1 | O60610 | Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) | Cancer-related genesDisease related genesHuman disease related genes | Fusion and delivery mediationImmune mediationMetabolism mediation | 2 | 0.50 | ||||
| DOCK8 | Q8NF50 | Dedicator of cytokinesis protein 8 | Disease related genesHuman disease related genesPredicted intracellular proteins | Adhesion and uptake mediationImmune mediationReceptor-signaling mediation | 2 | 0.50 | ||||
| EDNRB | P24530 | Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type) | Disease related genesFDA approved drug targetsG-protein coupled receptors | 7 | Cardiac arrhythmiaCardiovascular diseaseEncephalopathy | Clinical-translation mediationFusion and delivery mediationImmune mediation | 2 | 0.50 | ||
| EPHB2 | P29323 | Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2] | Cancer-related genesDisease related genesEnzymes | 1 | Kaposi sarcomaMelanomaPancreatic cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 2 | 0.50 |