Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
GBRG3Q99928Gamma-aminobutyric acid receptor subunit gamma-3 (GABA(A) receptor subunit gamma-3) (GABAAR subunit gamma-3)FDA approved drug targetsPredicted intracellular proteinsPredicted membrane proteins4Alzheimer diseaseAnxiety disorderCorneal diseaseClinical-translation mediationFusion and delivery mediationReceptor-signaling mediation10.50
GHRP10912Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]Disease related genesFDA approved drug targetsHuman disease related genes1COVID-19MalariaMiddle East Respiratory SyndromeAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
GLP2RO95838Glucagon-like peptide 2 receptor (GLP-2 receptor) (GLP-2-R) (GLP-2R)FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7Bowel habit changeDigestive system diseaseIndeterminate colitisClinical-translation mediationReceptor-signaling mediation10.50
GLRA2P23416Glycine receptor subunit alpha-2Disease related genesFDA approved drug targetsPredicted membrane proteins4Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation10.50
GLT11Q8NCW6Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)Disease related genesEnzymesMetabolic proteins1Metabolism mediation10.50
GNAQP50148Guanine nucleotide-binding protein G(q) subunit alpha (EC 3.6.5.-) (Guanine nucleotide-binding protein alpha-q)Cancer-related genesDisease related genesHuman disease related genesFusion and delivery mediationImmune mediationMetabolism mediation10.50
GP143P51810G-protein coupled receptor 143 (Ocular albinism type 1 protein)Disease related genesG-protein coupled receptorsHuman disease related genes7Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation10.50
GPIXP14770Platelet glycoprotein IX (GP-IX) (GPIX) (Glycoprotein 9) (CD antigen CD42a)CD markersDisease related genesHuman disease related genes1Clinical-translation mediationFusion and delivery mediationImmune mediation10.50
GPVIQ9HCN6Platelet glycoprotein VI (GPVI) (Glycoprotein 6)Disease related genesHuman disease related genesPlasma proteins1Arterial occlusive diseaseCerebral ischaemic strokeAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
GRIK1P39086Glutamate receptor ionotropic, kainate 1 (GluK1) (Excitatory amino acid receptor 3) (EAA3) (Glutamate receptor 5) (GluR-5) (GluR5)FDA approved drug targetsPredicted membrane proteins3Dissociative neurological symptom disorderEpilepsy/seizureGeneral pain disorderClinical-translation mediationFusion and delivery mediationReceptor-signaling mediation10.50
HFEQ30201Hereditary hemochromatosis protein (HLA-H)Disease related genesHuman disease related genesPredicted membrane proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
HTRA1Q92743Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)Disease related genesEnzymesHuman disease related genesOther mediation10.50
HYCCIQ9BYI3Hyccin (Down-regulated by CTNNB1 protein A)Disease related genesHuman disease related genesPredicted intracellular proteinsMetabolism mediation10.50
IGF1RP08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]Cancer-related genesCD markersDisease related genes1Adrenal cancerBreast cancerChronic kidney diseaseClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
IL21RQ9HBE5Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360)Cancer-related genesCD markersDisease related genes1Crohn diseasePostoperative inflammationSolid tumour/cancerClinical-translation mediationFusion and delivery mediationImmune mediation10.50
IL31RQ8NI17Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17)Disease related genesHuman disease related genesPredicted intracellular proteins1Fusion and delivery mediationImmune mediation10.50
IL6RBP40189Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)Cancer-related genesCandidate cardiovascular disease genesCD markers1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
INGR1P15260Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)CD markersDisease related genesFDA approved drug targets1Clinical-translation mediationImmune mediation10.50
ITA3P26006Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
ITA7Q13683Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]Disease related genesHuman disease related genesPotential drug targets1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
ITB2P05107Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)CD markersDisease related genesHuman disease related genes1Cerebral ischaemiaInnate/adaptive immunodeficiencyIschaemic/haemorrhagic strokeAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
ITB5P18084Integrin beta-5Cancer-related genesPlasma proteinsPredicted intracellular proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
ITB8P26012Integrin beta-8Cancer-related genesPredicted membrane proteins1Chronic kidney diseaseAdhesion and uptake mediationClinical-translation mediationImmune mediation10.50
IYD1Q6PHW0Iodotyrosine deiodinase 1 (IYD-1) (EC 1.21.1.1) (Iodotyrosine dehalogenase 1)Disease related genesEnzymesHuman disease related genes1Metabolism mediation10.50
JAG1P78504Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)CD markersDisease related genesHuman disease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50