Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
NHRF1O14745Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)Disease related genesHuman disease related genesPlasma proteinsFusion and delivery mediationReceptor-signaling mediation10.50
NK1RP25103Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7Abnormal micturitionAcute diabete complicationAcute upper respiratory infectionClinical-translation mediationFusion and delivery mediationImmune mediation10.50
NOS1P29475Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)Cancer-related genesEnzymesFDA approved drug targetsHeadacheMigraineClinical-translation mediationFusion and delivery mediationImmune mediation10.50
NPT2AQ06495Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (NaPi-3) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1)Disease related genesHuman disease related genesMetabolic proteins8Clinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
NPT2BO95436Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)Cancer-related genesDisease related genesHuman disease related genes8Lung cancerOvarian cancerClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
NTALQ9GZY6Linker for activation of T-cells family member 2 (Linker for activation of B-cells) (Membrane-associated adapter molecule) (Non-T-cell activation linker) (Williams-Beuren syndrome chromosomal region 15 protein) (Williams-Beuren syndrome chromosomal region 5 protein)Disease related genesHuman disease related genesPredicted intracellular proteins1Fusion and delivery mediationImmune mediationReceptor-signaling mediation10.50
OBSCNQ5VST9Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)Disease related genesEnzymesPlasma proteinsFusion and delivery mediationReceptor-signaling mediation10.50
OX2RO43614Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7DepressionInsomniaNarcolepsyClinical-translation mediationMetabolism mediationReceptor-signaling mediation10.50
PCD16Q96JQ0Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1)Disease related genesHuman disease related genesPlasma proteins1Adhesion and uptake mediation10.50
PCDGLQ9Y5F7Protocadherin gamma-C4 (PCDH-gamma-C4)Disease related genesPredicted intracellular proteinsPredicted membrane proteins1Adhesion and uptake mediation10.50
PCFTQ96NT5Proton-coupled folate transporter (HsPCFT) (hPCFT) (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1)Disease related genesEssential proteinsHuman disease related genes12Folate deficiency anaemiaLeukaemiaNutritional deficiencyClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
PD1L1Q9NZQ7Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
PDE3AQ14432cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)Disease related genesEnzymesFDA approved drug targets6Arterial occlusive diseaseAsthmaCardiovascular diseaseClinical-translation mediationReceptor-signaling mediation10.50
PI51AQ99755Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)Cancer-related genesEnzymesEssential proteinsAdhesion and uptake mediationImmune mediationMetabolism mediation10.50
PIEZ2Q9H5I5Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B)Disease related genesHuman disease related genesPotential drug targets38Fusion and delivery mediation10.50
PIGBQ92521GPI alpha-1,2-mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B)Disease related genesHuman disease related genesMetabolic proteins9Metabolism mediation10.50
PITM3Q9BZ71Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationMetabolism mediation10.50
PKP1Q13835Plakophilin-1 (Band 6 protein) (B6P)Disease related genesHuman disease related genesPlasma proteinsAdhesion and uptake mediationFusion and delivery mediation10.50
PLAKP14923Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)Cancer-related genesDisease related genesHuman disease related genesAdhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
PLCB4Q151471-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)Disease related genesEnzymesHuman disease related genesFusion and delivery mediationMetabolism mediationReceptor-signaling mediation10.50
PLD1Q13393Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)Disease related genesEnzymesHuman disease related genesFusion and delivery mediationImmune mediationMetabolism mediation10.50
PLPL9O6073385/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)Disease related genesEnzymesHuman disease related genes2Fusion and delivery mediationImmune mediationMetabolism mediation10.50
PLSLP13796Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)Cancer-related genesDisease related genesPlasma proteinsAdhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
POPD1Q8NE79Popeye domain-containing protein 1 (Popeye protein 1)Disease related genesHuman disease related genesPotential drug targets3Adhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation10.50
PPIP1O43586Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP)Disease related genesHuman disease related genesPredicted intracellular proteinsClinical-translation mediationFusion and delivery mediationImmune mediation10.50

351-375 of 792 proteins

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